Damyanov C, Radoslavova M, Gavrilov V, Stoeva D
Medical Center of Integrative Medicine, Sofia, Bulgaria.
J BUON. 2009 Oct-Dec;14(4):711-5.
Toxic effects and chemoresistance are serious problems concerning chemotherapy administration. Until now adequate solutions have not been found. In the past few years, while searching for possibilities to decrease toxicity, chemotherapy given in low, frequent doses - a novel strategy called "metronomic" administration - showed promising results. There is also another method for applying low doses of chemotherapeutics at short intervals, called Insulin Potential Therapy (IPT). It combines standard chemotherapy schemes, using lower doses of anticancer drugs and the hormone insulin which is administered intravenously (i.v.). We present hereby 3 cases of our original practice, which demonstrate the efficiency of IPT in the treatment of metastatic tumors, following failure of standard chemotherapy.
毒性作用和化疗耐药性是化疗给药过程中面临的严重问题。到目前为止，尚未找到合适的解决方案。在过去几年中，在寻找降低毒性的可能性时，低剂量、频繁给药的化疗——一种称为“节拍式”给药的新策略——显示出了有前景的结果。还有另一种在短时间间隔内应用低剂量化疗药物的方法，称为胰岛素潜能疗法（IPT）。它结合了标准化疗方案，使用较低剂量的抗癌药物和静脉注射（i.v.）的胰岛素。在此，我们展示3例我们的原始实践案例，这些案例证明了IPT在标准化疗失败后治疗转移性肿瘤方面的有效性。
