Yokota T, Fujii T, Roppongi T, Kanno K, Ogata T
Dept. of Surgery, Numata National Hospital.
Gan To Kagaku Ryoho. 1998 Apr;25(5):739-42.
A 59-year-old female complaining of breast tumor with suppurative discharge was diagnosed as having advanced breast cancer (T4cN3M1-StIV), with giant liver metastasis. Seven courses of combined chemoendocrine therapy (CTF + MPA) were used. Following the chemoendocrine therapy, primary tumor, lung, pleural, supraclavicular and parasternal metastasis disappeared, and the liver metastasis was obviously diminished. These effects continued for 1 year 7 months. Although CTF + MPA chemoendocrine therapy is widely used with advanced or recurrent breast cancer, a clearly effective case has almost never been reported. The reason for the remarkable effect in this case was the consistent immunity to breast cancer.
一名59岁女性,因乳腺肿瘤伴脓性分泌物就诊,被诊断为晚期乳腺癌(T4cN3M1-四期),伴有巨大肝转移。采用了七个疗程的联合化疗内分泌治疗(CTF + MPA)。化疗内分泌治疗后,原发肿瘤、肺、胸膜、锁骨上和胸骨旁转移灶消失,肝转移明显缩小。这些效果持续了1年7个月。虽然CTF + MPA化疗内分泌治疗广泛用于晚期或复发性乳腺癌,但几乎从未报道过明显有效的病例。该病例产生显著效果的原因是对乳腺癌的持续免疫。