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原发性皮肤癌肉瘤:皮肤镜和免疫组织化学特征。

Primary cutaneous carcinosarcoma: dermoscopic and immunohistochemical features.

机构信息

UT Southwestern Medical Center, Skin Surgery and Oncology Clinic, 5323 Harry Hines Blvd., Dallas, TX 75390, USA.

出版信息

Australas J Dermatol. 2010 Feb;51(1):26-8. doi: 10.1111/j.1440-0960.2009.00587.x.

Abstract

A 73-year-old man presented a 9-month history of an enlarging nodule on his right temple. Dermoscopy revealed a non-pigmented lesion with ulceration, fibrosis and pale globules. An excisional biopsy was carried out and histology showed a biphasic tumour with a basal cell carcinoma like epithelial component and a dermal undifferentiated sarcoma, with pleomorphic spindle cells and numerous osteoclast-like giant cells. Based on immunohistochemistry findings, a diagnosis of primary cutaneous carcinosarcoma was made and the patient underwent wide local excision.

摘要

一位 73 岁男性,右侧太阳穴处出现一个逐渐增大的结节,病程 9 个月。皮肤镜检查显示无色素性皮损,伴溃疡、纤维化和苍白小球。行切除活检,组织学检查显示为一种具有基底细胞癌样上皮成分和真皮未分化肉瘤的双相性肿瘤,伴有多形性梭形细胞和大量破骨样巨细胞。根据免疫组织化学检查结果,诊断为原发性皮肤癌肉瘤,患者接受了广泛局部切除术。

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