Bourgeault Emilie, Alain Jimmy, Gagné Eric
Department of Dermatology, Université Laval, Québec City, Canada
Department of Dermatology, Université Laval, Québec City, Canada.
J Cutan Med Surg. 2015 Jul-Aug;19(4):407-11. doi: 10.1177/1203475415575233. Epub 2015 Mar 5.
Cutaneous carcinosarcoma is a rare primary tumor of the skin, characterized by biphasic epithelial and mesenchymal differentiation.
Due to the limited number of cases reported, there is no consensus regarding treatment and prognosis. Some authors suggest that cutaneous carcinosarcomas should be viewed as aggressive tumors, with ancillary imaging used to evaluate potential metastatic disease. Other reports demonstrate an indolent disease course, especially with epidermal-type cutaneous carcinosarcomas.
We report a case of cutaneous carcinosarcoma, which we treated with electrodessication and curettage following a shave biopsy. The tumor had an epithelial component resembling a basal cell carcinoma and a fibrosarcomatous stroma.
At 1-year follow-up, our patient did not show evidence of recurrence or metastasis.
Our case suggests that a cutaneous carcinosarcoma with an epithelial component composed of basal cell carcinoma can be regarded as a high-risk nonmelanoma skin cancer.
皮肤癌肉瘤是一种罕见的原发性皮肤肿瘤，其特征为具有双相上皮和间充质分化。
由于报道的病例数量有限，关于治疗和预后尚无共识。一些作者认为皮肤癌肉瘤应被视为侵袭性肿瘤，需借助辅助成像评估潜在的转移性疾病。其他报告则显示其病程较为惰性，尤其是表皮型皮肤癌肉瘤。
我们报告一例皮肤癌肉瘤病例，在刮除活检后采用电干燥和刮除术进行治疗。该肿瘤具有类似基底细胞癌的上皮成分和纤维肉瘤样间质。
在1年的随访中，我们的患者未出现复发或转移迹象。
我们的病例表明，具有由基底细胞癌组成的上皮成分的皮肤癌肉瘤可被视为高危非黑色素瘤皮肤癌。
