Department of Psychiatry, University of California at San Diego, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0680, USA.
Bipolar Disord. 2010 Feb;12(1):45-55. doi: 10.1111/j.1399-5618.2009.00787.x.
This study assessed the relationship between multiple indicators of 'real-world' functioning and scores on a brief performance-based measure of functional capacity known as the Brief University of California San Diego (UCSD) Performance-based Skills Assessment (UPSA-B) in a sample of 205 patients with either serious bipolar disorder (n = 89) or schizophrenia (n = 116).
Participants were administered the UPSA-B and assessed on the following functional domains: (i) independent living status (e.g., residing independently as head of household, living in residential care facility); (ii) informant reports of functioning (e.g., work skills, daily living skills); (iii) educational attainment and estimated premorbid IQ as measured by years of education and Wide Range Achievement Test reading scores, respectively; and (iv) employment.
Better scores on the UPSA-B were associated with greater residential independence after controlling for age, diagnosis, and symptoms of psychopathology. Among both bipolar disorder and schizophrenia patients, higher UPSA-B scores were significantly related to better informant reports of functioning in daily living skills and work skills domains. Greater estimated premorbid IQ was associated with higher scores on the UPSA-B for both schizophrenia and bipolar disorder participants. Participants who were employed scored higher on the UPSA-B when controlling for age and diagnosis, but not when controlling for symptoms of psychopathology.
These data suggest the UPSA-B may be useful for assessing capacity for functioning in a number of domains in both people diagnosed with schizophrenia and bipolar disorder.
本研究评估了多项“真实世界”功能指标与简短的基于表现的功能能力评估(称为 Brief University of California San Diego [UCSD] Performance-based Skills Assessment [UPSA-B])之间的关系,该评估方法适用于 205 名严重双相情感障碍(n = 89)或精神分裂症(n = 116)患者。
参与者接受 UPSA-B 评估,并在以下功能领域进行评估:(i)独立生活状况(例如,作为户主独立居住,居住在住宿护理设施中);(ii)功能的知情者报告(例如,工作技能,日常生活技能);(iii)教育程度和估计的发病前智商,分别由受教育年限和广泛成就测试阅读分数衡量;以及(iv)就业。
在控制年龄、诊断和精神病理学症状后,UPSA-B 得分较高与更高的居住独立性相关。在双相情感障碍和精神分裂症患者中,UPSA-B 得分较高与日常生活技能和工作技能领域的功能知情者报告更好显著相关。较高的估计发病前智商与精神分裂症和双相情感障碍患者的 UPSA-B 得分较高相关。在控制年龄和诊断时,就业的参与者 UPSA-B 得分较高,但在控制精神病理学症状时则不然。
这些数据表明 UPSA-B 可能有助于评估诊断为精神分裂症和双相情感障碍的人群在多个领域的功能能力。