Moore Raeanne C, Fazeli Pariya L, Patterson Thomas L, Depp Colin A, Moore David J, Granholm Eric, Jeste Dilip V, Mausbach Brent T
Department of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA; The Sam and Rose Stein Institute for Research on Aging, University of California San Diego, La Jolla, CA, 92093, USA.
Department of Psychiatry, University of California San Diego, La Jolla, CA, 92093, USA.
Schizophr Res. 2015 May;164(1-3):187-92. doi: 10.1016/j.schres.2015.02.014. Epub 2015 Mar 16.
This study aimed to develop and validate a tablet mobile application version of the UCSD Performance-Based Skills Assessment (UPSA-M), a widely used test for assessing functional capacity in schizophrenia and other neurocognitively impaired patient populations.
The UPSA-M was developed for an iPad platform. Twenty-one middle-aged and older adults with schizophrenia and 13 healthy comparison (HC) participants completed a brief iPad tutorial, followed by the UPSA-M (full version, which includes all components of Brief UPSA-M) and a computer usage questionnaire. During a separate visit, patients with schizophrenia and HC participants completed the Brief UPSA (UPSA-B), and patients with schizophrenia completed a symptom inventory and brief neuropsychological screening battery.
The UPSA-M was feasible for use among middle aged and older adults with schizophrenia with no prior history of tablet usage. The UPSA-M was able to differentiate between schizophrenia and HC participants 80% of the time, and this differential ability increased to 87% with the UPSA-M Brief. Traditional UPSA scores, UPSA-B scores, and neuropsychological performance were related to UPSA-M scores, whereas symptoms of psychopathology, experience with tablet technology, or difficulties operating the device were not significantly associated with UPSA-M.
The UPSA-M performed just as well as the standard-of-practice version. These preliminary results indicate that the UPSA-M Brief has greater sensitivity than the full version of the UPSA-M, and carries the advantage of a shorter administration time. Overall, the UPSA-M appears to be a promising mobile tool to assess functional capacity.
本研究旨在开发并验证加州大学圣地亚哥分校基于表现的技能评估（UPSA-M）的平板电脑移动应用版本，UPSA-M是一种广泛用于评估精神分裂症及其他神经认知功能受损患者群体功能能力的测试。
UPSA-M是为iPad平台开发的。21名患有精神分裂症的中老年成年人和13名健康对照（HC）参与者完成了一个简短的iPad教程，随后进行了UPSA-M（完整版，包括简短UPSA-M的所有组件）和一份电脑使用问卷。在另一次就诊时，精神分裂症患者和HC参与者完成了简短UPSA（UPSA-B），精神分裂症患者完成了症状清单和简短神经心理筛查量表。
UPSA-M在没有平板电脑使用史的精神分裂症中老年成年人中使用是可行的。UPSA-M在80%的时间里能够区分精神分裂症患者和HC参与者，使用UPSA-M简版时这种区分能力提高到了87%。传统UPSA分数、UPSA-B分数和神经心理表现与UPSA-M分数相关，而精神病理学症状、平板电脑技术使用经验或设备操作困难与UPSA-M没有显著关联。
UPSA-M的表现与实践标准版本一样好。这些初步结果表明，UPSA-M简版比UPSA-M完整版具有更高的敏感性，并且具有给药时间更短的优势。总体而言，UPSA-M似乎是一种很有前景的用于评估功能能力的移动工具。
