Paediatric Surgery and Urology Department, Hopital Mère-Enfant, CHU de NANTES, 44 093 Nantes Cedex, France.
J Pediatr Urol. 2010 Aug;6(4):338-45. doi: 10.1016/j.jpurol.2010.01.006. Epub 2010 Feb 10.
Non-neurogenic elimination disorders cover a wide spectrum of lower urinary tract and bowel dysfunctions, observed in the absence of a neurological background or lower urinary tract malformation. We reviewed conditions responsible for incontinence during bladder filling with normal voiding patterns (such as overactive bladder, giggle incontinence, post-void dribbling), and dysfunctional voiding syndromes. Dysfunctional elimination syndrome usually includes detrusor-sphincter dyscoordination, small-capacity overactive bladder or decompensated large poorly contractile bladder, and large-volume post-micturition residuals, occasionally associated with bowel dysfunction. At the most severe end of the spectrum lies the non-neurogenic neurogenic bladder syndrome, characterized by the association of a severe impairment of the upper urinary tract with a dysfunctional elimination syndrome. It must be emphasized that if the term 'non-neurogenic' relates to the absence of a neurological lesion, it is however conceivable that these conditions actually do have an underlying neurological cause that remains to be identified.
非神经源性排尿障碍涵盖了广泛的下尿路和肠道功能障碍，这些障碍在没有神经背景或下尿路畸形的情况下观察到。我们回顾了在正常排尿模式下充盈膀胱时导致失禁的情况（如过度活动膀胱、笑失禁、排尿后滴沥），以及排尿功能障碍综合征。排尿功能障碍综合征通常包括逼尿肌括约肌协同失调、小容量活动过度膀胱或代偿不良的大无收缩力膀胱，以及大量残余尿量，偶尔伴有肠道功能障碍。在该谱的最严重端是无神经源性神经源性膀胱综合征，其特征是上尿路严重受损与排尿功能障碍综合征相关联。必须强调的是，如果“非神经源性”一词与缺乏神经病变有关，那么这些情况实际上可能确实有一个尚未确定的潜在神经原因。
