Department of Family and Community Medicine, University of California, San Francisco, California, USA.
Diabetes Care. 2010 May;33(5):1034-6. doi: 10.2337/dc09-2175. Epub 2010 Feb 11.
To clarify previous findings that diabetes distress is related to glycemic control and self-management whereas measures of depression are not, using both binary and continuous measures of depression.
Four hundred and sixty-three type 2 patients completed measures of diabetes distress (Diabetes Distress Scale [DDS]) and clinical depression (Patient Health Questionnaire 8 [PHQ8]). PHQ8 was employed as either a binary (>or=10) or continuous variable. Dependent variables were A1C, diet, physical activity (PA), and medication adherence (MA).
The inclusion of a binary or continuous PHQ8 score yielded no differences in any equation. DDS was significantly associated with A1C and PA, whereas PHQ8 was not; both DDS and PHQ8 were significantly and independently associated with diet and MA.
The lack of association between depression and glycemic control is not due to the use of a binary measure of depression. Findings further clarify the significant association between distress and A1C.
使用抑郁的二分类和连续测量方法，阐明先前发现的糖尿病困扰与血糖控制和自我管理有关，而抑郁的测量指标则没有。
463 例 2 型糖尿病患者完成了糖尿病困扰量表（DDS）和临床抑郁量表（PHQ8）的测量。PHQ8 采用二分类（>=10）或连续变量。依赖变量为 A1C、饮食、体力活动（PA）和药物依从性（MA）。
纳入二分类或连续 PHQ8 评分对任何方程均无差异。DDS 与 A1C 和 PA 显著相关，而 PHQ8 则不相关；DDS 和 PHQ8 均与饮食和 MA 显著且独立相关。
抑郁与血糖控制之间缺乏关联并不是因为使用了抑郁的二分类测量方法。研究结果进一步阐明了困扰与 A1C 之间的显著关联。
