Departamento de Quimica Organica, Facultad de Ciencias, Universidad de Granada, ES-18071 Granada, Spain.
Chem Biodivers. 2010 Feb;7(2):421-39. doi: 10.1002/cbdv.200900023.
Starting from solid wastes from two-phase olive-oil extraction, the pentacyclic triterpenes oleanolic acid and maslinic acid were isolated. These natural compounds were transformed into methyl olean-12-en-28-oate (5), which then was transformed into several seco-C-ring triterpene compounds by chemical and photolytic modifications. The triene seco-products were fragmented through several oxidative procedures to produce, simultaneously, cis- and trans-decalin derivatives, both potential synthons for bioactive compounds. The chemical behavior of the isolated fragments was investigated, and a suitable approach to several low-molecular-weight terpenes was performed. These are interesting processes for the value-addition to solid waste from the olive-oil industry.
从两相橄榄油提取的固体废物中，分离出五环三萜酸齐墩果酸和马栗树皮酸。这些天然化合物被转化为甲基齐墩果酸-12-烯-28-酸甲酯（5），然后通过化学和光解修饰转化为几种 secoc 环三萜化合物。三烯 sec 产物通过几种氧化程序进行断裂，同时产生顺式和反式十氢萘衍生物，它们都是生物活性化合物的潜在前体。研究了分离片段的化学行为，并采用了一种合适的方法来制备几种低分子量萜烯。这些过程对于提高橄榄油工业固体废物的附加值具有重要意义。
