Laser-Forschungslabor im LIFE-Zentrum der LMU München, München, Germany.
J Biophotonics. 2010 Jun;3(5-6):269-76. doi: 10.1002/jbio.200900097.
Endovenous laser therapy (ELT) was introduced in clinical practice as a therapy for incompetent veins about ten years ago. One characteristic of ELT is the broad spectrum of different treatment protocols by means of a variety of laser systems as well as manifold application forms and dosimetry concepts are under investigations. Clinical results with effective, relatively pain-free occlusion of incompetent varicosis veins have been observed, as well as undesired side effects such as ecchymosis, phlebitis and recanalization. In recent years systematic experimental investigations and the analysis of clinical results have increased the understanding of the interrelation between the clinical and physical aspects, followed to a continuous optimization of ELT. The use of IR wavelengths and radial irradiation concepts, together with continuous moving of the optical fiber seem to reduce possible side effects. This way ELT treatment becomes a more standardized effective method for the treatment of varicose veins. In future controlled randomized studies are required to compare optimized ELT treatment with other endoluminal modalities as well as conventional surgery.
大约十年前，静脉内激光治疗（ELT）作为一种治疗功能不全静脉的疗法被引入临床实践。ELT 的一个特点是，通过各种激光系统以及多种应用形式和剂量学概念，可以进行广泛的不同治疗方案。已经观察到有效的、相对无痛的功能不全静脉曲张闭塞的临床结果，以及瘀斑、静脉炎和再通等不良副作用。近年来，系统的实验研究和临床结果分析增加了对临床和物理方面相互关系的理解，从而不断优化 ELT。使用 IR 波长和放射状照射概念，以及连续移动光纤似乎可以减少可能的副作用。这样，ELT 治疗成为一种更标准化的治疗静脉曲张的有效方法。未来需要进行对照随机研究，将优化的 ELT 治疗与其他腔内治疗方式以及传统手术进行比较。
