Truong Van Gia, Tran Van Nam, Hwang Jieun, Kang Hyun Wook
Interdisciplinary Program of Marine-Bio, Electrical & Mechanical Engineering, Pukyong National University, Busan, South Korea.
Center for Marine-Integrated Biomedical Technology (BK21 Plus), Pukyong National University, Busan, South Korea.
Biomed Opt Express. 2018 Jun 8;9(7):3037-3048. doi: 10.1364/BOE.9.003037. eCollection 2018 Jul 1.
The aim of the current study is to investigate the effect of radial and cylindrical light distributions on the response of vascular tissue during 1470-nm irradiation in models. Due to a low irradiance (5.3 W/cm) and wide light distribution, cylindrically diffusing irradiation yielded uniform thermal coagulation while radial irradiation accompanied delamination of layers in leporine veins. Bovine foot model testing verified that the diffusing irradiation was associated with the steady maximum temperature and no tissue attachment, compared with the radial irradiation. The proposed cylindrical light application can be a feasible way to treat varicose veins in an effective manner.
本研究的目的是在模型中研究径向和圆柱形光分布对1470纳米照射期间血管组织反应的影响。由于低辐照度（5.3瓦/平方厘米）和宽光分布，圆柱形漫射照射产生均匀的热凝固，而径向照射则伴随着兔静脉中层的分层。牛足模型测试证实，与径向照射相比，漫射照射与稳定的最高温度和无组织附着有关。所提出的圆柱形光应用可能是一种有效治疗静脉曲张的可行方法。
