Antoshina L I, Pavlovskaia N A
Med Tr Prom Ekol. 2009(12):22-7.
The authors studied influence of vibration on some serum biochemical values. Oxidative stress and muscular tissue parameters appeared to be the earliest indicators to change. Preclinical stage of vibration disease is characterized by lower activity of superoxide dismutase, increased urinary levels of creatinine and CCr coefficient. Slight increase in serum catalase activity is seen. These parameters increase in vibration disease patients. Urinary creatinine level remains high in some individuals with residual manifestations of vibration disease, after the exposure. Serum levels of copper, ceruloplasmin, potassium, sodium, cholinesterase activity are changed insignificantly under influence of vibration. The authors calculated occurrence of individuals who demonstrate abnormal changes of the stated parameters.
作者研究了振动对某些血清生化值的影响。氧化应激和肌肉组织参数似乎是最早发生变化的指标。振动病的临床前期表现为超氧化物歧化酶活性降低、尿肌酐水平升高和肌酐清除率系数增加。血清过氧化氢酶活性略有升高。这些参数在振动病患者中会增加。在接触振动后，一些有振动病残留表现的个体尿肌酐水平仍然很高。在振动的影响下，血清铜、铜蓝蛋白、钾、钠、胆碱酯酶活性的变化不显著。作者计算了表现出所述参数异常变化的个体的发生率。
