Heaton Lisa J, McNeil Daniel W, Milgrom Peter
Dental Fears Research Clinic, Department of Dental Public Health Sciences, Box 357475, University of Washington, Seattle, WA 98195-7475, USA.
SAAD Dig. 2010 Jan;26:27-35.
Extensive research and clinical experience have demonstrated the usefulness of sedation in helping fearful patients receive dental treatment, particularly when they have urgent treatment needs. In addition, the efficacy of behavioural programmes for managing dental fears is well established. While often these two approaches are seen as oppositional, our work in Seattle, Morgantown and at King's College London Dental Institute demonstrates the complementarity of the two approaches. Using the example of two compounds, one very familiar, propranolol, and one that has recently become of interest, D-cycloserine, we wish to illustrate the manner in which these medications can be used to enhance behavioural approaches to managing dental anxiety.
广泛的研究和临床经验表明，镇静有助于恐惧的患者接受牙科治疗，尤其是当他们有紧急治疗需求时。此外，管理牙科恐惧的行为方案的有效性已得到充分证实。虽然这两种方法通常被视为相互对立，但我们在西雅图、摩根敦以及伦敦国王学院牙科学院的工作表明了这两种方法的互补性。以两种化合物为例，一种非常常见的普萘洛尔，以及一种最近引起关注的D-环丝氨酸，我们希望说明这些药物可用于增强管理牙科焦虑的行为方法的方式。
