Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Immunity. 2010 Jan 29;32(1):11-3. doi: 10.1016/j.immuni.2010.01.001.
In this issue of Immunity, Hegazy et al. (2010) report that in response to lymphocytic choriomeningitis virus (LCMV) infection, fully differentiated virus-specific Th2 cells can be reprogrammed into GATA-3(+)T-bet(+) cells capable of producing both interleukin-4 and interferon-gamma.
在本期《免疫》中,Hegazy 等人(2010)报告称,在淋巴细胞脉络丛脑膜炎病毒(LCMV)感染后,完全分化的病毒特异性 Th2 细胞可被重新编程为 GATA-3(+)T-bet(+)细胞,能够同时产生白细胞介素-4 和干扰素-γ。