• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.

作者信息

Mosmann T R, Coffman R L

机构信息

DNAX Research Institute, Palo Alto, California 94304.

出版信息

Annu Rev Immunol. 1989;7:145-73. doi: 10.1146/annurev.iy.07.040189.001045.

DOI:10.1146/annurev.iy.07.040189.001045
PMID:2523712
Abstract
摘要

相似文献

1
TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties.辅助性T细胞1型和辅助性T细胞2型：不同的淋巴因子分泌模式导致不同的功能特性。
Annu Rev Immunol. 1989;7:145-73. doi: 10.1146/annurev.iy.07.040189.001045.
2
Membranes from both Th1 and Th2 T cell clones stimulate B cell proliferation and prepare B cells for lymphokine-induced differentiation to secrete Ig.来自Th1和Th2 T细胞克隆的细胞膜均能刺激B细胞增殖，并使B细胞为淋巴因子诱导的分化以分泌免疫球蛋白做好准备。
J Immunol. 1991 Dec 1;147(11):3696-702.
3
Cognate interactions between helper T cells and B cells. V. Reconstitution of T helper cell function using purified plasma membranes from activated Th1 and Th2 T helper cells and lymphokines.辅助性T细胞与B细胞之间的同源相互作用。五、利用来自活化的Th1和Th2辅助性T细胞的纯化质膜及淋巴因子重建辅助性T细胞功能。
J Immunol. 1991 Feb 15;146(4):1118-24.
4
Differences between T helper cell type I (Th1) and Th2 cell lines in signalling pathways for induction of contact-dependent T cell help.I型辅助性T细胞（Th1）和Th2细胞系在诱导接触依赖性T细胞辅助信号通路中的差异。
Eur J Immunol. 1992 Jan;22(1):85-93. doi: 10.1002/eji.1830220114.
5
Characterization of T helper 1 and 2 cell subsets in normal mice. Helper T cells responsible for IL-4 and IL-5 production are present as precursors that require priming before they develop into lymphokine-secreting cells.正常小鼠中辅助性T细胞1和2亚群的特征。负责产生白细胞介素-4和白细胞介素-5的辅助性T细胞以前体形式存在，在发育成分泌淋巴因子的细胞之前需要启动。
J Immunol. 1988 Nov 15;141(10):3445-55.
6
Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness.辅助/诱导性T淋巴细胞的异质性。I. 淋巴因子的产生及淋巴因子反应性。
J Exp Med. 1987 Dec 1;166(6):1774-87. doi: 10.1084/jem.166.6.1774.
7
Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells.淋巴因子介导的辅助性T细胞1和辅助性T细胞2克隆增殖反应的调控
J Exp Med. 1988 Aug 1;168(2):543-58. doi: 10.1084/jem.168.2.543.
8
Autoreactive T cell clones isolated from normal and autoimmune-susceptible mice exhibit lymphokine secretory and functional properties of both Th1 and Th2 cells.从正常和自身免疫易感小鼠中分离出的自身反应性T细胞克隆表现出Th1和Th2细胞的淋巴因子分泌及功能特性。
Clin Immunol Immunopathol. 1990 Oct;57(1):148-62. doi: 10.1016/0090-1229(90)90030-t.
9
T cell induction of macrophage IL-1 during antigen presentation. Characterization of a lymphokine mediator and comparison of TH1 and TH2 subsets.
J Immunol. 1989 May 15;142(10):3469-76.
10
Pharmacologic modulation of Th1- and Th2-associated lymphokine production.
Life Sci. 1993;53(26):1921-34. doi: 10.1016/0024-3205(93)90014-t.

引用本文的文献

1
Comparative immunogenicity study of two different types of tuberculosis vaccines based on a heterologous boosting strategy.基于异源加强策略的两种不同类型结核疫苗的比较免疫原性研究
Arch Microbiol. 2025 Sep 15;207(10):262. doi: 10.1007/s00203-025-04463-4.
2
Targeting macrophage phenotypes to prevent diseases caused by and infections.针对巨噬细胞表型以预防由[具体病原体]感染引起的疾病。 （你原文中“and”前后内容缺失，请补充完整以便准确翻译）
Front Immunol. 2025 Aug 7;16:1595954. doi: 10.3389/fimmu.2025.1595954. eCollection 2025.
3
A novel adjuvant system BK-02 with CpG2006 and MF59 enhances the immunogenicity of a herpes zoster subunit vaccine.
一种含有CpG2006和MF59的新型佐剂系统BK-02增强了带状疱疹亚单位疫苗的免疫原性。
Front Immunol. 2025 Jul 15;16:1641109. doi: 10.3389/fimmu.2025.1641109. eCollection 2025.
4
A novel in vivo adjuvant activity of hydrocarbon isolated from Hippophae rhamnoides.从沙棘中分离出的烃类物质的一种新型体内佐剂活性。
Inflammopharmacology. 2025 Jul 12. doi: 10.1007/s10787-025-01825-8.
5
Induction of systemic and mucosal immune response against Zika virus by vaccination with non-infectious chimeric VLPs.通过接种非感染性嵌合病毒样颗粒诱导针对寨卡病毒的全身和黏膜免疫反应。
Sci Rep. 2025 Jul 10;15(1):24834. doi: 10.1038/s41598-025-07059-6.
6
Beyond T-cell subsets: stemness and adaptation redefining immunity and immunotherapy.超越T细胞亚群：干性与适应性重新定义免疫及免疫疗法
Cell Mol Immunol. 2025 Jul 10. doi: 10.1038/s41423-025-01321-7.
7
Innate Immune Mechanisms in Normal and Adverse Pregnancy.正常与不良妊娠中的先天免疫机制
Adv Exp Med Biol. 2025;1476:339-379. doi: 10.1007/978-3-031-85340-1_14.
8
Neuro-immune crosstalk in cancer: mechanisms and therapeutic implications.癌症中的神经-免疫相互作用：机制与治疗意义
Signal Transduct Target Ther. 2025 Jun 2;10(1):176. doi: 10.1038/s41392-025-02241-8.
9
Immunological biomarkers and their role in the diagnosis and prognosis of leishmaniasis: A case-control study.免疫学生物标志物及其在利什曼病诊断和预后中的作用：一项病例对照研究。
Trop Parasitol. 2025 Jan-Jun;15(1):33-41. doi: 10.4103/tp.tp_57_24. Epub 2025 Apr 5.
10
Decoding mechanisms and protein markers in lung-brain axis.肺-脑轴中的解码机制和蛋白质标志物
Respir Res. 2025 May 19;26(1):190. doi: 10.1186/s12931-025-03272-z.