Department of Evidence-Based Medicine, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishi Road, Beijing 100037, PR China.
Clin Nutr. 2010 Apr;29(2):192-8. doi: 10.1016/j.clnu.2009.06.008. Epub 2010 Feb 12.
BACKGROUND & AIMS: We aimed to estimate appropriate cutoff of hypertriglyceridemic waist (HTGW) designated for impaired fasting glucose (IFG)/diabetes mellitus (DM) and to evaluate the association between HTGW and fasting glucose, IFG and DM, respectively.
A cross-sectional survey in a nationally representative sample of 15,540 Chinese adults aged 35-74 years was conducted during 2000-2001.
Appropriate cutoffs of HTGW designated both for IFG and DM was triglyceride> or =110mg/dl and waist circumference> or =75cm both among men and women. Overall 35.4% of men as well as 33.6% of women had HTGW. Moreover 30.8%, 7.2% of men with HTGW as well as 30.0%, 9.7% of women had IFG and DM, respectively. Furthermore multivariate models revealed that adjusted odds ratios of IFG and DM were 2.7 (1.7, 2.5) and 2.6 (1.8, 3.8) for men with HTGW as well as 1.7 (1.4, 2.1) and 3.6 (2.5, 5.1) for women, respectively.
As the phenotype of visceral obesity HTGW was more common among Chinese adults. Global lifestyle modification should be targeted at adults with HTGW to prevent the premature incidence of DM and reduce the burden in future in China.
本研究旨在评估适合中国成年人的高甘油三酯血症性腰围（HTGW）切点，以识别空腹血糖受损（IFG）/糖尿病（DM）患者，并分别评价 HTGW 与空腹血糖、IFG 和 DM 的关系。
该研究采用 2000-2001 年全国代表性样本的横断面调查，共纳入 15540 名 35-74 岁成年人。
男女 HTGW 切点均为甘油三酯≥110mg/dl 且腰围≥75cm。总体上，35.4%的男性和 33.6%的女性存在 HTGW。此外，30.8%和 7.2%的男性以及 30.0%和 9.7%的女性存在 IFG 和 DM。多变量模型显示，HTGW 使男性 IFG 和 DM 的调整比值比分别升高至 2.7（1.7，2.5）和 2.6（1.8，3.8），HTGW 使女性 IFG 和 DM 的调整比值比分别升高至 1.7（1.4，2.1）和 3.6（2.5，5.1）。
HTGW 是中国成年人内脏性肥胖的一种表型，更为常见。全球生活方式的改变应针对 HTGW 人群，以预防 DM 的早发，减轻中国未来的疾病负担。
