Díaz-Santana Mary Vanellys, Suárez Pérez Erick L, Ortiz Martínez Ana P, Guzmán Serrano Manuel, Pérez Cardona Cynthia M
Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, Medical Sciences Campus, San Juan, PR, USA.
Department of Public Health, School of Public Health and Health Sciences, University of Massachusetts, 408 Arnold House, 715N. Pleasant Street, Amherst, MA, 01003-9304, USA.
J Immigr Minor Health. 2016 Feb;18(1):102-9. doi: 10.1007/s10903-014-9985-y.
This study assessed the association of the hypertriglyceridemic waist (HTGW) phenotype with prediabetes and diabetes (DM) in a group of Hispanics. Analysis of a cross-sectional study of 858 adults residing in Puerto Rico that collected data on blood pressure, biochemical, and anthropometric measurements was performed. HTGW phenotype was defined as elevated triglycerides and elevated waist circumference. Prediabetes was defined as a fasting glucose of 100-125 mg/dL and DM as a fasting glucose ≥126 mg/dL or prior diagnosis. Prevalence of HTGW, prediabetes, and DM was 27.9, 38.0, and 21.6 %, respectively. Subjects with the HTGW phenotype had higher adjusted odds of prediabetes (POR 5.55; 95 % CI 3.38-9.13) and DM (POR 7.28; 95 % CI 3.63-14.63) compared to those without the phenotype. The association for prediabetes was stronger for women than among men. HTGW phenotype was strongly associated with prediabetes and DM, reinforcing the need to further assess its performance as a screening tool to identify at-risk individuals for cardiometabolic conditions.
本研究评估了一组西班牙裔人群中高甘油三酯腰围（HTGW）表型与糖尿病前期及糖尿病（DM）之间的关联。对居住在波多黎各的858名成年人进行了横断面研究分析，收集了血压、生化指标和人体测量数据。HTGW表型定义为甘油三酯升高和腰围增大。糖尿病前期定义为空腹血糖100 - 125mg/dL，糖尿病定义为空腹血糖≥126mg/dL或既往诊断。HTGW、糖尿病前期和糖尿病的患病率分别为27.9%、38.0%和21.6%。与无该表型的受试者相比，具有HTGW表型的受试者患糖尿病前期（比值比5.55；95%可信区间3.38 - 9.13）和糖尿病（比值比7.28；95%可信区间3.63 - 14.63）的调整后几率更高。糖尿病前期的关联在女性中比在男性中更强。HTGW表型与糖尿病前期和糖尿病密切相关，这进一步表明有必要进一步评估其作为识别心血管代谢疾病高危个体的筛查工具的性能。
