Leslie DanFaculty of Pharmacy, University of Toronto, Toronto, Canada.
Can Fam Physician. 2010 Feb;56(2):143-4.
In addition to suffering from nausea and vomiting of pregnancy, which is being treated with antiemetics, some of my pregnant patients complain of heartburn and acid reflux. Should these symptoms also be treated and, if so, which acid-reducing medications are safe for use during pregnancy?
Increased severity of nausea and vomiting of pregnancy is associated with the presence of heartburn and acid reflux. Antacids, histamine-2 receptor antagonists, and proton pump inhibitors can be used safely during pregnancy, as large studies have been published with no evidence of adverse fetal effects.
除了正在接受止吐药物治疗的妊娠恶心和呕吐外，我的一些孕妇患者还抱怨烧心和胃酸反流。这些症状也应该治疗吗？如果需要治疗，哪些减少胃酸的药物在怀孕期间使用是安全的？
妊娠恶心和呕吐的严重程度增加与烧心和胃酸反流的存在有关。抗酸剂、组胺 2 受体拮抗剂和质子泵抑制剂在怀孕期间均可安全使用，因为已经发表了大量研究，没有证据表明对胎儿有不良影响。
