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新生大鼠和成年大鼠淋巴细胞中的三碘甲状腺原氨酸受体

Triiodothyronine receptors in lymphocytes of newborn and adult rats.

作者信息

Csaba G, Sudár F, Dobozy O

出版信息

Horm Metab Res. 1977 Nov;9(6):499-501. doi: 10.1055/s-0028-1093509.

DOI:10.1055/s-0028-1093509
PMID:201551
Abstract

Cytoplasmic and nuclear incorporation of 125I triiodothyronine by thymic lymphocytes has been demonstrated by electron microscopic autoradiography. Incorporation was significantly more pronounced in the newborn than in the adult age. The information emerging from the experime,tal observations contributes further evidence to the more precise interpretation of receptor maturation.

摘要

通过电子显微镜放射自显影术已证实胸腺淋巴细胞对125I三碘甲状腺原氨酸的细胞质和细胞核摄取。摄取在新生儿中比在成年期明显更显著。从实验观察中得出的信息为更精确地解释受体成熟提供了进一步的证据。

相似文献

1
Triiodothyronine receptors in lymphocytes of newborn and adult rats.新生大鼠和成年大鼠淋巴细胞中的三碘甲状腺原氨酸受体
Horm Metab Res. 1977 Nov;9(6):499-501. doi: 10.1055/s-0028-1093509.
2
Differentiation dependent alterations in lymphocytic triiodothyronine reception.淋巴细胞三碘甲状腺原氨酸受体的分化依赖性改变。
Horm Metab Res. 1978 Sep;10(5):455-6. doi: 10.1055/s-0028-1095845.
3
Contributions of plasma triiodothyronine and local thyroxine monodeiodination to triiodothyronine to nuclear triiodothyronine receptor saturation in pituitary, liver, and kidney of hypothyroid rats. Further evidence relating saturation of pituitary nuclear triiodothyronine receptors and the acute inhibition of thyroid-stimulating hormone release.甲状腺功能减退大鼠垂体、肝脏和肾脏中血浆三碘甲状腺原氨酸及局部甲状腺素单碘脱碘作用对三碘甲状腺原氨酸与核三碘甲状腺原氨酸受体饱和的贡献。关于垂体细胞核三碘甲状腺原氨酸受体饱和与促甲状腺激素释放急性抑制之间关系的进一步证据。
J Clin Invest. 1978 May;61(5):1247-59. doi: 10.1172/JCI109041.
4
Partial peripheral resistance to thyroid hormones, a post-receptor defect?甲状腺激素的部分外周抵抗,一种受体后缺陷?
Horm Metab Res Suppl. 1984;14:20-3.
5
Nuclear receptors and thyroid hormone action: a progress report.核受体与甲状腺激素作用:进展报告
Fed Proc. 1979 Jul;38(8):2154-61.
6
Humoral modulation of hepatic nuclear triiodothyronine receptors in the cross-circulated rat.交叉循环大鼠肝脏核三碘甲状腺原氨酸受体的体液调节
Horm Metab Res. 1982 Apr;14(4):224. doi: 10.1055/s-2007-1018977.
7
Modulation of nuclear receptor affinity for 3,5,3'-triiodothyronine by nucleotide in vitro.
Endocrinol Exp. 1985 Dec;19(4):245-51.
8
Nuclear binding of triiodothyronine in human mononuclear cells, and lymphocytes in culture.三碘甲状腺原氨酸在人单核细胞及培养的淋巴细胞中的核结合。
Acta Endocrinol Suppl (Copenh). 1983;251:16-20.
9
Ontogenesis of 3,5,3'-triiodothyronine receptors in neonatal rat brain: dissociation between receptor concentration and stimulation of oxygen consumption by 3,5,3'-triiodothyronine.
Endocrinology. 1978 Sep;103(3):943-8. doi: 10.1210/endo-103-3-943.
10
Triiodothyronine (T3) receptors in brain and liver during induced hypothyroidism in rats [proceedings].
Arch Int Physiol Biochim. 1979 Feb;87(1):172-3.

引用本文的文献

1
Peripheral insensitivity to thyroid hormones in a euthyroid girl with goitre.一名甲状腺肿的甲状腺功能正常女孩对外周甲状腺激素不敏感。
Arch Dis Child. 1980 Mar;55(3):207-12. doi: 10.1136/adc.55.3.207.
2
Binding of (125I) triiodothyronine to human peripheral leukocytes and its internalization.(125I)三碘甲状腺原氨酸与人外周血白细胞的结合及其内化
Experientia. 1987 Oct 15;43(10):1117-8. doi: 10.1007/BF01956056.
3
Influence of serotonin on the immune response.血清素对免疫反应的影响。
Immunology. 1985 Mar;54(3):505-12.
4
Receptor ontogeny and hormonal imprinting.受体个体发生与激素印记。
Experientia. 1986 Jul 15;42(7):750-9. doi: 10.1007/BF01941521.