General Medicine Research Unit, Butler Hospital, Providence, RI 02906, USA.
J Addict Dis. 2009 Jul;28(3):219-25. doi: 10.1080/10550880903014155.
Sleep disturbance among methadone-maintained patients is highly prevalent. A full understanding of sleep disturbance requires polysomnographic measures along with subjective sleep quality measures. The goal of this study was to describe the authors' experiences in performing at-home unattended polysomnography in this population. Participants had a Pittsburgh Sleep Quality Index score of six or higher, which indicates clinically significant insomnia, and 65% of eligible individuals agreed to enroll. Among 88 participants (53% female, 82% white, and a mean methadone dose of 105 mg/day), each undergoing two nights of home polysomnography, we initiated 165 of a maximum of 176 recordings. Overall, 81.7% of participants provided at least one night of "acceptable" polysomnographic data of at least 4 hours duration. Urine toxicology on polysomnographic nights demonstrated that benzodiazepine use was common. The authors conclude that unattended polysomnography is feasible in a population of individuals receiving methadone maintenance treatment. Polysomnography signal quality and overall study success rates were similar to those in non-substance using populations.
美沙酮维持治疗患者的睡眠障碍发生率很高。要全面了解睡眠障碍,需要进行多导睡眠图测量,并结合主观睡眠质量测量。本研究的目的是描述作者在该人群中进行家庭无人值守多导睡眠图的经验。参与者的匹兹堡睡眠质量指数得分在 6 分或以上,这表明存在临床显著的失眠,有 65%符合条件的人同意参与。在 88 名参与者中(53%为女性,82%为白人,美沙酮平均剂量为 105 毫克/天),每人均进行了两晚的家庭多导睡眠图检查,我们启动了最多 176 次记录中的 165 次。总体而言,81.7%的参与者至少提供了一晚持续时间至少 4 小时的“可接受”多导睡眠图数据。多导睡眠图检查当晚的尿液毒理学检测表明,苯二氮䓬类药物的使用很常见。作者得出结论,无人值守的多导睡眠图在接受美沙酮维持治疗的人群中是可行的。多导睡眠图信号质量和总体研究成功率与非物质使用人群相似。