Gallo Marco, Riddle Donald L
Department of Medical Genetics, Faculty of Medicine, 263-2185 East Mall, The University of British Columbia, Vancouver, BC V6T1Z4, Canada.
J Biol. 2010;9(1):7. doi: 10.1186/jbiol215. Epub 2010 Feb 10.
The nematode Caenorhabditis elegans is a favorite model for the study of aging. A wealth of genetic and genomic studies show that metabolic regulation is a hallmark of life-span modulation. A recent study in BMC Biology identifying metabolic signatures for longevity suggests that amino-acid pools may be important in longevity.
线虫秀丽隐杆线虫是研究衰老的常用模式生物。大量的遗传学和基因组学研究表明,代谢调节是寿命调节的一个标志。《BMC生物学》最近的一项确定长寿代谢特征的研究表明,氨基酸库可能在长寿中起重要作用。