Health Services Research and Development Service, Durham Veterans Affairs Medical Center , Durham, North Carolina 27705, USA.
J Rheumatol. 2010 Apr;37(4):842-50. doi: 10.3899/jrheum.090302. Epub 2010 Feb 15.
This cross-sectional study examined associations of occupational tasks with radiographic and symptomatic osteoarthritis (OA) in a community-based sample.
Participants from the Johnston County Osteoarthritis Project (n = 2729) self-reported the frequency of performing 10 specific occupational tasks at the longest job ever held (never/seldom/sometimes vs often/always) and lifetime exposure to jobs that required spending > 50% of their time doing 5 specific tasks or lifting 22, 44, or 110 pounds 10 times weekly. Multivariable logistic regression models examined associations of each occupational task separately with radiographic and symptomatic knee and hip OA, controlling for age, race, gender, body mass index, prior knee or hip injury, and smoking.
Radiographic hip and knee OA were not significantly associated with any occupational tasks, but several occupational tasks were associated with increased odds of both symptomatic knee and hip OA: lifting > 10 pounds, crawling, and doing heavy work while standing (OR 1.4-2.1). More occupational walking and standing and less sitting were also associated with symptomatic knee OA, and more bending/twisting/reaching was associated with symptomatic hip OA. Exposure to a greater number of physically demanding occupational tasks at the longest job was associated with greater odds of both symptomatic knee and hip OA.
Our results confirm an association of physically demanding occupational tasks with both symptomatic knee and hip OA, including several specific activities that increased the odds of OA in both joint groups. These tasks represent possibilities for identifying and targeting at-risk individuals with preventive interventions.
本横断面研究调查了职业任务与社区样本中影像学和症状性骨关节炎(OA)之间的关联。
约翰斯顿县骨关节炎项目的参与者(n=2729)自我报告了在最长的工作中执行 10 项特定职业任务的频率(从不/很少/有时与经常/总是),以及一生中从事需要花费> 50%的时间从事 5 项特定任务或每周举起重物 22、44 或 110 磅 10 次的工作的暴露情况。多变量逻辑回归模型分别检查了每种职业任务与影像学和症状性膝和髋 OA 的关联,控制了年龄、种族、性别、体重指数、既往膝或髋损伤以及吸烟情况。
影像学髋和膝 OA 与任何职业任务均无显著关联,但某些职业任务与症状性膝和髋 OA 的发生风险增加有关:举起重物> 10 磅、爬行和站立时进行重体力劳动(OR 1.4-2.1)。更多的职业行走和站立以及更少的坐着与症状性膝 OA 有关,更多的弯曲/扭曲/伸展与症状性髋 OA 有关。在最长的工作中接触到更多体力要求高的职业任务与症状性膝和髋 OA 的发生风险增加有关。
我们的结果证实了体力要求高的职业任务与症状性膝和髋 OA 之间存在关联,包括增加两个关节组 OA 发生风险的几种特定活动。这些任务为识别和针对具有预防性干预措施的高危个体提供了可能性。