Gaudet P, Lane L, Fey P, Bridge A, Poux S, Auchincloss A, Axelsen K, Braconi Quintaje S, Boutet E, Brown P, Coudert E, Datta R S, de Lima W C, de Oliveira Lima T, Duvaud S, Farriol-Mathis N, Ferro Rojas S, Feuermann M, Gateau A, Hinz U, Hulo C, James J, Jimenez S, Jungo F, Keller G, Lemercier P, Lieberherr D, Moinat M, Nikolskaya A, Pedruzzi I, Rivoire C, Roechert B, Schneider M, Stanley E, Tognolli M, Sjölander K, Bougueleret L, Chisholm R L, Bairoch A
dictyBase, Northwestern University Biomedical Informatics Center and Center for Genetic Medicine, Chicago, IL 60611, USA, Swiss-Prot group, Swiss Institute of Bioinformatics, CMU, 1 Rue Michel Servet, 1211 Geneva 4, Switzerland, The EMBL Outstation, The European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK, QB3 Institute and Department of Bioengineering, University of California, Berkeley, CA, USA, Department of Cellular Physiology and Metabolism, University of Geneva, CMU, 1 Rue Michel Servet, 1211 Geneva 4, Switzerland, Protein Information Resource, Georgetown University Medical Center, 3300 Whitehaven St NW, Suite 1200, Washington DC 20007, USA and Department of Structural Biology and Bioinformatics, University of Geneva, CMU, 1 Rue Michel Servet, 1211 Geneva 4, Switzerland.
Database (Oxford). 2009;2009:bap016. doi: 10.1093/database/bap016. Epub 2009 Oct 15.
UniProtKB/Swiss-Prot, a curated protein database, and dictyBase, the Model Organism Database for Dictyostelium discoideum, have established a collaboration to improve data sharing. One of the major steps in this effort was the 'Dicty annotation marathon', a week-long exercise with 30 annotators aimed at achieving a major increase in the number of D. discoideum proteins represented in UniProtKB/Swiss-Prot. The marathon led to the annotation of over 1000 D. discoideum proteins in UniProtKB/Swiss-Prot. Concomitantly, there were a large number of updates in dictyBase concerning gene symbols, protein names and gene models. This exercise demonstrates how UniProtKB/Swiss-Prot can work in very close cooperation with model organism databases and how the annotation of proteins can be accelerated through those collaborations.
蛋白质信息数据库（UniProtKB/Swiss-Prot）是一个经过整理的蛋白质数据库，而盘基网柄菌模式生物数据库（dictyBase）则是针对盘基网柄菌的数据库。二者已建立合作关系以改善数据共享。这项工作的主要步骤之一是“盘基网柄菌注释马拉松”，这是一项为期一周的活动，有30名注释员参与，旨在大幅增加蛋白质信息数据库（UniProtKB/Swiss-Prot）中所代表的盘基网柄菌蛋白质数量。这次马拉松活动使得蛋白质信息数据库（UniProtKB/Swiss-Prot）中对1000多种盘基网柄菌蛋白质进行了注释。与此同时，盘基网柄菌数据库（dictyBase）在基因符号、蛋白质名称和基因模型方面有大量更新。这项活动展示了蛋白质信息数据库（UniProtKB/Swiss-Prot）如何与模式生物数据库密切合作，以及如何通过这些合作加速蛋白质注释。
