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阿波罗：一个序列注释编辑器。

Apollo: a sequence annotation editor.

作者信息

Lewis S E, Searle S M J, Harris N, Gibson M, Lyer V, Richter J, Wiel C, Bayraktaroglu L, Birney E, Crosby M A, Kaminker J S, Matthews B B, Prochnik S E, Smithy C D, Tupy J L, Rubin G M, Misra S, Mungall C J, Clamp M E

机构信息

Department of Molecular and Cellular Biology, Life Sciences Addition, University of California, Berkeley, CA 94720-3200, USA.

出版信息

Genome Biol. 2002;3(12):RESEARCH0082. doi: 10.1186/gb-2002-3-12-research0082. Epub 2002 Dec 23.

DOI:10.1186/gb-2002-3-12-research0082
PMID:12537571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC151184/
Abstract

The well-established inaccuracy of purely computational methods for annotating genome sequences necessitates an interactive tool to allow biological experts to refine these approximations by viewing and independently evaluating the data supporting each annotation. Apollo was developed to meet this need, enabling curators to inspect genome annotations closely and edit them. FlyBase biologists successfully used Apollo to annotate the Drosophila melanogaster genome and it is increasingly being used as a starting point for the development of customized annotation editing tools for other genome projects.

摘要

用于注释基因组序列的纯计算方法存在已久的不准确性，这就需要一个交互式工具，以便生物学专家通过查看和独立评估支持每个注释的数据来完善这些近似值。开发Apollo就是为了满足这一需求，使注释人员能够仔细检查基因组注释并进行编辑。FlyBase的生物学家成功地使用Apollo对黑腹果蝇基因组进行了注释，并且它越来越多地被用作其他基因组项目定制注释编辑工具开发的起点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1153/151184/7bc408bd01b4/gb-2002-3-12-research0082-11.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1153/151184/89ce438a87c2/gb-2002-3-12-research0082-9.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1153/151184/7bc408bd01b4/gb-2002-3-12-research0082-11.jpg

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