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Inhibition of S6K by resveratrol: in search of the purpose.

作者信息

Blagosklonny Mikhail V

机构信息

Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.

出版信息

Aging (Albany NY). 2009 Jun 29;1(6):511-4. doi: 10.18632/aging.100059.

DOI:10.18632/aging.100059
PMID:20157534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2806036/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af0b/2806036/ec1240447a16/aging-01-511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af0b/2806036/ec1240447a16/aging-01-511-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af0b/2806036/ec1240447a16/aging-01-511-g001.jpg

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本文引用的文献

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2
Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy.白藜芦醇对哺乳动物S6激酶的抑制作用会抑制自噬。
Aging (Albany NY). 2009 Jun 3;1(6):515-28. doi: 10.18632/aging.100056.
3
Growth and aging: a common molecular mechanism.生长与衰老：一种共同的分子机制。
Aging (Albany NY). 2016 Oct 25;8(10):2568-2589. doi: 10.18632/aging.101090.
4
Longevity extension by phytochemicals.植物化学物质对寿命的延长作用。
Molecules. 2015 Apr 13;20(4):6544-72. doi: 10.3390/molecules20046544.
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Xenohormetic and anti-aging activity of secoiridoid polyphenols present in extra virgin olive oil: a new family of gerosuppressant agents.存在于特级初榨橄榄油中的环烯醚萜多酚的外激素和抗衰老活性：一类新型的衰老抑制剂。
Cell Cycle. 2013 Feb 15;12(4):555-78. doi: 10.4161/cc.23756. Epub 2013 Jan 31.
6
CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis.CDK 抑制剂（p16/p19/p21）可诱导肿瘤相关成纤维细胞衰老和自噬，通过旁分泌相互作用“促进”肿瘤生长，而不会增加新生血管形成。
Cell Cycle. 2012 Oct 1;11(19):3599-610. doi: 10.4161/cc.21884. Epub 2012 Aug 30.
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Interspecies Chemical Signals Released into the Environment May Create Xenohormetic, Hormetic and Cytostatic Selective Forces that Drive the Ecosystemic Evolution of Longevity Regulation Mechanisms.释放到环境中的种间化学信号可能会产生外源性、激素和细胞抑制选择性力量，从而推动长寿调控机制的生态系统进化。
Dose Response. 2012;10(1):75-82. doi: 10.2203/dose-response.11-011.Titorenko. Epub 2011 Jul 27.
8
Hormesis does not make sense except in the light of TOR-driven aging.除了从TOR驱动的衰老角度来看，兴奋效应是没有意义的。
Aging (Albany NY). 2011 Nov;3(11):1051-62. doi: 10.18632/aging.100411.
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PLoS One. 2011;6(10):e26405. doi: 10.1371/journal.pone.0026405. Epub 2011 Oct 28.
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Polyamines in aging and disease.衰老与疾病中的多胺
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Aging (Albany NY). 2009 Apr 20;1(4):357-62. doi: 10.18632/aging.100040.
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Prevention of cancer by inhibiting aging.通过抑制衰老预防癌症。
Cancer Biol Ther. 2008 Oct;7(10):1520-4. doi: 10.4161/cbt.7.10.6663. Epub 2008 Oct 21.