Univ. Bordeaux, Institut des Sciences Moléculaires & Institut Européen de Chimie et Biologie, Pessac, France.
Angew Chem Int Ed Engl. 2012 Jul 9;51(28):6824-6. doi: 10.1002/anie.201203059. Epub 2012 Jun 21.
A votre Santé! The mechanism by which resveratrol, a hydroxystilbenoid polyphenol found in grapes and present in wine, exerts antiaging metabolic benefits has been uncovered. Chung and co-workers have found that it works by inhibiting cAMP phosphodiesterases, thus triggering a signaling cascade that leads to the possible activation of the mammalian enzyme sirtuin 1.
祝您健康!白藜芦醇是一种在葡萄中发现的、存在于葡萄酒中的羟基二苯乙烯多酚,其发挥抗衰老代谢益处的机制已被揭示。钟博士及其同事发现,它通过抑制 cAMP 磷酸二酯酶来发挥作用,从而触发信号级联反应,可能导致哺乳动物酶 sirtuin 1 的激活。