Saito T, Duly D, Williams R J
Inorganic Chemistry Laboratory, University of Oxford, UK.
Eur J Biochem. 1991 Apr 10;197(1):39-42. doi: 10.1111/j.1432-1033.1991.tb15879.x.
There are 12 histidine residues/molecule in the iron-uptake regulation protein (Fur). Here we examine their pH dependence using proton nuclear magnetic resonance spectroscopy. The histidines have widely spread acid dissociation constants but we can not offer a simple explantation for their complicated behaviour.