激光、干细胞与 COPD
Lasers, stem cells, and COPD.
机构信息
Entest BioMedical, San Diego, CA, USA.
出版信息
J Transl Med. 2010 Feb 16;8:16. doi: 10.1186/1479-5876-8-16.
Abstract
The medical use of low level laser (LLL) irradiation has been occurring for decades, primarily in the area of tissue healing and inflammatory conditions. Despite little mechanistic knowledge, the concept of a non-invasive, non-thermal intervention that has the potential to modulate regenerative processes is worthy of attention when searching for novel methods of augmenting stem cell-based therapies. Here we discuss the use of LLL irradiation as a "photoceutical" for enhancing production of stem cell growth/chemoattractant factors, stimulation of angiogenesis, and directly augmenting proliferation of stem cells. The combination of LLL together with allogeneic and autologous stem cells, as well as post-mobilization directing of stem cells will be discussed.
摘要
低水平激光（LLL）照射在医学上的应用已经有几十年的历史了，主要集中在组织愈合和炎症等领域。尽管对其作用机制的了解甚少，但这种非侵入性、非热干预的概念，有可能调节再生过程，因此在寻找增强基于干细胞的治疗方法时值得关注。在这里，我们讨论了将低水平激光照射作为一种“光药”来增强干细胞生长/趋化因子的产生、刺激血管生成，并直接增强干细胞的增殖。我们还将讨论低水平激光照射与同种异体和自体干细胞的联合应用，以及动员后对干细胞的定向作用。
相似文献
1
Lasers, stem cells, and COPD.激光、干细胞与 COPD
J Transl Med. 2010 Feb 16;8:16. doi: 10.1186/1479-5876-8-16.
2
Role of Stem Cells in the Pathogenesis of Chronic Obstructive Pulmonary Disease and Pulmonary Emphysema.干细胞在慢性阻塞性肺疾病和肺气肿发病机制中的作用
COPD. 2018 Oct;15(5):536-556. doi: 10.1080/15412555.2018.1536116. Epub 2018 Nov 23.
3
Human adipose-derived stem cell spheroid treated with photobiomodulation irradiation accelerates tissue regeneration in mouse model of skin flap ischemia.经光生物调节照射处理的人脂肪来源干细胞球体可加速皮瓣缺血小鼠模型中的组织再生。
Lasers Med Sci. 2017 Nov;32(8):1737-1746. doi: 10.1007/s10103-017-2239-1. Epub 2017 Jun 27.
4
Laser biomodulation of normal and neoplastic cells.激光对正常细胞和肿瘤细胞的生物调节。
Lasers Med Sci. 2012 Sep;27(5):1039-43. doi: 10.1007/s10103-011-1040-9. Epub 2011 Dec 29.
5
Combined effects of electromagnetic field and low-level laser increase proliferation and alter the morphology of human adipose tissue-derived mesenchymal stem cells.电磁场和低强度激光的联合作用可增加人脂肪组织来源间充质干细胞的增殖并改变其形态。
Lasers Med Sci. 2017 Jan;32(1):151-160. doi: 10.1007/s10103-016-2097-2. Epub 2016 Oct 21.
6
Stem cell therapy in stroke.中风的干细胞治疗。
Cell Mol Life Sci. 2009 Mar;66(5):757-72. doi: 10.1007/s00018-008-8346-1.
7
Low intensity lasers differently induce primary human osteoblast proliferation and differentiation.低强度激光以不同方式诱导原代人成骨细胞的增殖和分化。
J Photochem Photobiol B. 2016 Oct;163:14-21. doi: 10.1016/j.jphotobiol.2016.08.006. Epub 2016 Aug 6.
8
Preconditioning With Low-Level Laser Irradiation Enhances the Therapeutic Potential of Human Adipose-derived Stem Cells in a Mouse Model of Photoaged Skin.低水平激光辐射预处理增强人脂肪来源干细胞在光老化皮肤小鼠模型中的治疗潜力。
Photochem Photobiol. 2018 Jul;94(4):780-790. doi: 10.1111/php.12912. Epub 2018 Apr 21.
9
A preliminary comparison between the effects of red and infrared laser irradiation on viability and proliferation of SHED.红色激光与红外激光照射对脱落乳牙干细胞活力及增殖影响的初步比较
Lasers Med Sci. 2019 Apr;34(3):465-471. doi: 10.1007/s10103-018-2615-5. Epub 2018 Aug 18.
10
The clinical use of regenerative therapy in COPD.再生疗法在 COPD 中的临床应用。
Int J Chron Obstruct Pulmon Dis. 2014 Dec 12;9:1389-96. doi: 10.2147/COPD.S49519. eCollection 2014.
引用本文的文献
1
The Role of Laser and Microwave in Treatment of Endocrine Disorders: A Systematic Review.激光和微波在治疗内分泌疾病中的作用：一项系统评价
J Lasers Med Sci. 2024 Jul 23;15:e23. doi: 10.34172/jlms.2024.23. eCollection 2024.
2
Regenerative medicine in lung diseases: A systematic review.肺部疾病中的再生医学：一项系统综述。
Front Vet Sci. 2023 Jan 17;10:1115708. doi: 10.3389/fvets.2023.1115708. eCollection 2023.
3
Efficacy of Low-Level Laser Therapy in a Rabbit Model of Rhinosinusitis.低水平激光疗法治疗兔鼻窦炎模型的疗效。
Int J Mol Sci. 2023 Jan 1;24(1):760. doi: 10.3390/ijms24010760.
4
Ultrasonographic and electrophysiological outcomes of carpal tunnel syndrome treated with low-level laser therapy: A double-blind, prospective, randomized, sham-controlled study.低强度激光治疗腕管综合征的超声和电生理结果：一项双盲、前瞻性、随机、假对照研究。
Arch Rheumatol. 2021 Oct 13;37(1):19-30. doi: 10.46497/ArchRheumatol.2022.8605. eCollection 2022 Mar.
5
The Functions and Mechanisms of Low-Level Laser Therapy in Tendon Repair (Review).低强度激光疗法在肌腱修复中的作用及机制（综述）
Front Physiol. 2022 Feb 15;13:808374. doi: 10.3389/fphys.2022.808374. eCollection 2022.
6
Low-Level Laser Therapy: Potential and Complications.低强度激光疗法：潜力与并发症
J Lasers Med Sci. 2021 Aug 4;12:e42. doi: 10.34172/jlms.2021.42. eCollection 2021.
7
Photobiomodulation Regulation as One Promising Therapeutic Approach for Myocardial Infarction.光生物调节作为一种有前途的心肌梗死治疗方法。
Oxid Med Cell Longev. 2021 Jul 17;2021:9962922. doi: 10.1155/2021/9962922. eCollection 2021.
8
Photobiomodulation combined with adipose-derived stem cells encapsulated in methacrylated gelatin hydrogels enhances in vivo bone regeneration.光生物调节联合包被于甲基丙烯酰化明胶水凝胶中的脂肪源性干细胞增强体内骨再生。
Lasers Med Sci. 2022 Feb;37(1):595-606. doi: 10.1007/s10103-021-03308-y. Epub 2021 Apr 11.
9
Effectiveness of low-level laser therapy on recovery from neurosensory disturbance after sagittal split ramus osteotomy: a systematic review and meta-analysis.下颌升支矢状劈开截骨术后神经感觉障碍恢复中低强度激光治疗的有效性：一项系统评价和荟萃分析
Maxillofac Plast Reconstr Surg. 2020 Dec 17;42(1):41. doi: 10.1186/s40902-020-00285-0.
10
Evaluation of Laser Effects on the Human Body After Laser Therapy.激光治疗后激光对人体影响的评估。
J Lasers Med Sci. 2020 Winter;11(1):91-97. doi: 10.15171/jlms.2020.15. Epub 2020 Jan 18.
本文引用的文献
1
Galectin-1 and semaphorin-3A are two soluble factors conferring T-cell immunosuppression to bone marrow mesenchymal stem cell.半乳糖凝集素-1 和 Sema3A 是赋予骨髓间充质干细胞 T 细胞免疫抑制功能的两种可溶性因子。
Stem Cells Dev. 2010 Jul;19(7):1075-9. doi: 10.1089/scd.2009.0212.
2
Anti-inflammatory effect of low-level laser and light-emitting diode in zymosan-induced arthritis.低强度激光和发光二极管对酵母聚糖诱导性关节炎的抗炎作用
Photomed Laser Surg. 2010 Apr;28(2):227-32. doi: 10.1089/pho.2008.2422.
3
Low level laser irradiation precondition to create friendly milieu of infarcted myocardium and enhance early survival of transplanted bone marrow cells.低水平激光辐射预处理可创造梗死心肌的友好微环境，提高移植骨髓细胞的早期存活率。
J Cell Mol Med. 2010 Jul;14(7):1975-87. doi: 10.1111/j.1582-4934.2009.00886.x. Epub 2009 Sep 1.
4
Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.间充质干细胞经气道给药可预防新生大鼠肺损伤中肺泡生长停滞。
Am J Respir Crit Care Med. 2009 Dec 1;180(11):1131-42. doi: 10.1164/rccm.200902-0179OC. Epub 2009 Aug 27.
5
Bone marrow stromal cells attenuate lung injury in a murine model of neonatal chronic lung disease.骨髓基质细胞减轻新生小鼠慢性肺病模型中的肺损伤。
Am J Respir Crit Care Med. 2009 Dec 1;180(11):1122-30. doi: 10.1164/rccm.200902-0242OC. Epub 2009 Aug 27.
6
An evidence-based approach to patient selection for laser vision correction.一种基于证据的激光视力矫正患者选择方法。
J Refract Surg. 2009 Jul;25(7 Suppl):S661-7. doi: 10.3928/1081597X-20090611-07.
7
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters.瘦而非肥胖的个体中，脂肪富含一群独特的调节性T细胞，这些细胞会影响代谢参数。
Nat Med. 2009 Aug;15(8):930-9. doi: 10.1038/nm.2002. Epub 2009 Jul 26.
8
Phototherapy promotes healing of chronic diabetic leg ulcers that failed to respond to other therapies.光疗可促进对其他治疗无反应的慢性糖尿病腿部溃疡的愈合。
Lasers Surg Med. 2009 Aug;41(6):433-41. doi: 10.1002/lsm.20789.
9
Low-level laser irradiation promotes the recovery of atrophied gastrocnemius skeletal muscle in rats.低强度激光照射促进大鼠萎缩腓肠肌骨骼肌的恢复。
Exp Physiol. 2009 Sep;94(9):1005-15. doi: 10.1113/expphysiol.2009.047738. Epub 2009 Jun 12.
10
May oxygen-ozone therapy improves cardiovascular disorders?臭氧疗法能改善心血管疾病吗？
Cardiovasc Hematol Disord Drug Targets. 2009 Jun;9(2):78-85. doi: 10.2174/187152909788488681.
Zotero 插件