Khalkhal Ensieh, Razzaghi Mohammadreza, Rostami-Nejad Mohammad, Rezaei-Tavirani Majid, Heidari Beigvand Hazhir, Rezaei Tavirani Mostafa
Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Laser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
J Lasers Med Sci. 2020 Winter;11(1):91-97. doi: 10.15171/jlms.2020.15. Epub 2020 Jan 18.
Lasers have wide applications in the treatment and diagnosis of diseases and various medical fields. Laser therapy like the other methods has advantages and disadvantages. Some risks such as bleeding, pain, and infection are created after laser therapy. Explanation and evaluation of laser effects on cell function, tissue, and the body are the aims of this study. We reviewed papers available from 1986 to 2019 about the effects of lasers on cells and tissue. An online search of PubMed, Science Direct and Google scholar using such keywords as "laser", "cell", "tissue", "body" and "side effects" was performed. The laser photons are absorbed by chromophores, resulting in the target heating and localized damage. Laser irradiation alters cellular metabolism and cellular functions. These alterations may be accompanied by undesired side effects which can be monitored via metabolites level change in the body. Based on this finding, laser therapy may be associated with several side effects and complications; therefore, before treatment, the determination of laser types and their properties is necessary to avoid creating side effects. The advantages and disadvantages of the treatment type should be considered in order to choose the best treatment with the least side effects. The patients' awareness of possible side effects before treatment and also an effective follow-up and management of patients after action are two important points in laser therapy. Training curriculum definition should be determined for laser applicant qualifications in different medical fields.
激光在疾病治疗、诊断及各种医学领域有着广泛应用。与其他方法一样,激光疗法有其优缺点。激光治疗后会产生一些风险,如出血、疼痛和感染。本研究的目的是解释和评估激光对细胞功能、组织和身体的影响。我们回顾了1986年至2019年期间有关激光对细胞和组织影响的论文。通过使用“激光”“细胞”“组织”“身体”和“副作用”等关键词,在PubMed、Science Direct和谷歌学术上进行了在线搜索。激光光子被发色团吸收,导致目标加热和局部损伤。激光照射会改变细胞代谢和细胞功能。这些改变可能伴有不良副作用,可通过体内代谢物水平变化进行监测。基于这一发现,激光治疗可能会伴有多种副作用和并发症;因此,在治疗前,确定激光类型及其特性对于避免产生副作用很有必要。为了选择副作用最小的最佳治疗方法,应考虑治疗类型的优缺点。治疗前让患者了解可能的副作用以及治疗后对患者进行有效的随访和管理是激光治疗中的两个要点。应确定针对不同医学领域激光从业者资质的培训课程定义。