Bilodeau Elizabeth, Alawi Faizan, Costello Bernard J, Prasad Joanne L
Department of Oral and Maxillofacial Surgery, University of Pittsburgh School of Dental Medicine, 3501 Terrace Street, Pittsburgh, PA 15261, USA.
Oral Maxillofac Surg Clin North Am. 2010 Feb;22(1):183-94. doi: 10.1016/j.coms.2009.10.006.
Molecular diagnostic techniques are quickly finding a role in the detection and diagnosis of tumors, and in predicting their behavior. They may also prove useful in developing new therapeutic approaches to head and neck cancer. The surgeon working in the craniomaxillofacial region should have an understanding of these technologies, their availability in various settings, and how they affect various aspects of treatment, particularly in the detection and treatment of malignancies. This article offers an overview of recent advances in molecular diagnostic techniques, with their implications for diagnosis and management of head and neck tumors.
分子诊断技术正在迅速在肿瘤的检测、诊断以及预测其行为方面发挥作用。它们在开发头颈部癌症的新治疗方法中也可能被证明是有用的。在颅颌面区域工作的外科医生应该了解这些技术、它们在不同环境中的可用性，以及它们如何影响治疗的各个方面，特别是在恶性肿瘤的检测和治疗方面。本文概述了分子诊断技术的最新进展及其对头颈部肿瘤诊断和管理的意义。
