Buckley Michael J, Beckman Eric J
University of Pittsburgh School of Dental Medicine, 3501 Terrace Street, Pittsburgh, PA 15213, USA.
Oral Maxillofac Surg Clin North Am. 2010 Feb;22(1):195-9. doi: 10.1016/j.coms.2009.10.008.
Presently, tissue adhesives and sealants have limited use in oral and maxillofacial surgical procedures. Skin closure occurs regularly with cyanoacrylate adhesives. Sealing of dural tears in conjunction with dural closure has been shown to be very successful. With the development of more head and neck reconstructive procedures and cosmetic procedures, demand will increase for better surgical adhesives. Clinical trials are beginning for newly developed adhesives with the chemical characterizations, the safe reabsorptive profile, and the adhesive strength necessary to benefit oral and maxillofacial surgery patients in the near future. Adhesives for bone fixation, while in early development, also show a promising chemical profile and will be of significant benefit to oral and maxillofacial surgical patients.
目前,组织粘合剂和密封剂在口腔颌面外科手术中的应用有限。氰基丙烯酸酯粘合剂常用于皮肤闭合。硬膜撕裂的密封结合硬膜闭合已被证明非常成功。随着更多头颈重建手术和美容手术的发展,对更好的手术粘合剂的需求将会增加。针对新开发的具有化学特性、安全吸收特性以及在不久的将来使口腔颌面外科患者受益所需的粘合强度的粘合剂的临床试验正在展开。用于骨固定的粘合剂虽然尚处于早期开发阶段,但也显示出有前景的化学特性,并且将对口腔颌面外科患者有显著益处。