静电纺丝硅酸盐纤维基底的热处理增强了细胞的黏附和增殖。
Heat treatment of electrospun silicate fiber substrates enhances cellular adhesion and proliferation.
机构信息
Biotechnology and Food Research Institute, Fukuoka Industrial Technology Center, 1465-5 Aikawa, Kurume, Fukuoka 839-0861, Japan.
出版信息
J Biosci Bioeng. 2010 Mar;109(3):304-6. doi: 10.1016/j.jbiosc.2009.08.482. Epub 2009 Sep 17.
PMID:20159582
Abstract
Synthetic scaffolds support cell attachment in vitro. We prepared ultra-fine silicate fibers using the sol-gel process and electrospinning, heated the fibers to 500 degrees C and investigated their effects on the behavior of human hepatocellular carcinoma (HepG2) cells. Alterations in surface composition following heat treatment improved cell adhesion and influenced cell migration.
摘要
合成支架支持细胞在体外附着。我们使用溶胶-凝胶法和静电纺丝制备了超精细硅酸盐纤维，将纤维加热到 500 摄氏度，并研究了它们对人肝癌（HepG2）细胞行为的影响。热处理后表面成分的改变改善了细胞黏附，并影响了细胞迁移。
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