University of Minnesota, Minneapolis,Minnesota, USA.
Am J Epidemiol. 2010 Mar 15;171(6):701-8. doi: 10.1093/aje/kwp452. Epub 2010 Feb 16.
Soft drinks and other sweetened beverages may contribute to risk of type 2 diabetes and obesity. However, research has not addressed higher risk and Asian populations. The authors examined the association between soft drinks and juice and the risk of type 2 diabetes among Chinese Singaporeans enrolled in a prospective cohort study of 43,580 participants aged 45-74 years and free of diabetes and other chronic diseases at baseline. The incidence of physician-diagnosed type 2 diabetes was assessed by interview and validated; 2,273 participants developed diabetes during follow-up. After adjustment for potential lifestyle and dietary confounders, participants consuming > or =2 soft drinks per week had a relative risk of type 2 diabetes of 1.42 (95% confidence interval (CI): 1.25, 1.62) compared with those who rarely consumed soft drinks. Similarly, consumption of > or =2 juice beverages per week was associated with an increased risk (relative risk (RR) = 1.29, 95% CI: 1.05, 1.58). The association was modified by 5-year weight gain for > or =2 soft drinks per week among those who gained > or =3 kg (RR = 1.70, 95% CI: 1.34, 2.16) compared with those who gained less weight (RR = 1.20, 95% CI: 1.03, 1.41). Relatively frequent intake of soft drinks and juice is associated with an increased risk for development of type 2 diabetes in Chinese men and women.
软饮料和其他含糖饮料可能会增加 2 型糖尿病和肥胖的风险。然而，研究尚未涉及到更高的风险和亚洲人群。作者研究了软饮料和果汁与中国新加坡人 2 型糖尿病风险之间的关系，该研究纳入了 43580 名年龄在 45-74 岁、基线时无糖尿病和其他慢性病的前瞻性队列研究参与者。通过访谈和验证评估了医生诊断的 2 型糖尿病的发病率；2273 名参与者在随访期间患上了糖尿病。在调整了潜在的生活方式和饮食混杂因素后，每周饮用>或=2 份软饮料的参与者患 2 型糖尿病的相对风险为 1.42（95%置信区间：1.25，1.62），而很少饮用软饮料的参与者相对风险为 1.00。同样，每周饮用>或=2 份果汁饮料与风险增加相关（相对风险（RR）=1.29，95%置信区间：1.05，1.58）。对于每周饮用>或=2 份软饮料且体重增加>或=3kg 的参与者，体重增加>或=3kg 的参与者的相关性更强（RR=1.70，95%置信区间：1.34，2.16），而体重增加较少的参与者的相关性较弱（RR=1.20，95%置信区间：1.03，1.41）。在男性和女性中，相对频繁地摄入软饮料和果汁与 2 型糖尿病的发生风险增加有关。
