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病理性赌博:生物学与临床考量

Pathological Gambling: Biological and Clinical Considerations.

作者信息

Topf Jocelyn L, Yip Sarah W, Potenza Marc N

机构信息

Departments of Psychiatry and Child Study Center, Yale University School of Medicine, Connecticut Mental Health Center, New Haven, CT, United States.

出版信息

J Addict Med. 2009 Sep 1;3(3):111-119. doi: 10.1097/ADM.0b013e31819b7bff.

DOI:10.1097/ADM.0b013e31819b7bff
PMID:20161094
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2744972/
Abstract

Pathological gambling (PG) is categorized as an impulse control disorder (ICD). Phenomenological, neurobiological and pharmacological data suggest similarities in the pathophysiologies of substance use disorders (SUDs) and PG. Both behavioral and pharmacological approaches, including those that have been empirically validated for SUDs, have shown promise in the treatment of PG. Findings from biological studies of PG are reviewed, and treatment approaches based on controlled studies are summarized.

摘要

病理性赌博(PG)被归类为一种冲动控制障碍(ICD)。现象学、神经生物学和药理学数据表明,物质使用障碍(SUDs)和PG在病理生理学上存在相似之处。行为疗法和药物疗法,包括那些已在SUDs中得到实证验证的方法,在PG治疗中都显示出了前景。本文回顾了PG生物学研究的结果,并总结了基于对照研究的治疗方法。

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本文引用的文献

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A cross-sectional study of problem and pathological gambling in patients with schizophrenia/schizoaffective disorder.一项关于精神分裂症/分裂情感性障碍患者问题赌博和病理性赌博的横断面研究。
J Clin Psychiatry. 2009 Sep;70(9):1250-7. doi: 10.4088/JCP.08m04359. Epub 2009 Jun 16.
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Review. The neurobiology of pathological gambling and drug addiction: an overview and new findings.综述:病理性赌博与药物成瘾的神经生物学:概述与新发现
Philos Trans R Soc Lond B Biol Sci. 2008 Oct 12;363(1507):3181-9. doi: 10.1098/rstb.2008.0100.
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Predicting response to opiate antagonists and placebo in the treatment of pathological gambling.预测阿片类拮抗剂和安慰剂在病理性赌博治疗中的反应。
Psychopharmacology (Berl). 2008 Nov;200(4):521-7. doi: 10.1007/s00213-008-1235-3. Epub 2008 Jun 26.
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A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges.一项关于阿片类拮抗剂纳曲酮治疗病理性赌博冲动的双盲、安慰剂对照研究。
J Clin Psychiatry. 2008 May;69(5):783-9. doi: 10.4088/jcp.v69n0511.
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Altered CSF 5-HIAA Disposition in Pathologic Male Gamblers.病理性男性赌徒脑脊液 5-HIAA 分布改变。
CNS Spectr. 1999 Dec;4(12):25-33. doi: 10.1017/s1092852900006799.
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A double-blind, placebo-controlled trial of olanzapine for the treatment of video poker pathological gamblers.一项关于奥氮平治疗视频扑克病理性赌博者的双盲、安慰剂对照试验。
Pharmacol Biochem Behav. 2008 May;89(3):298-303. doi: 10.1016/j.pbb.2007.12.025. Epub 2008 Jan 7.
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