在温和条件下硫介导的羧酸与异腈的双组分偶联反应。
Thio-mediated two-component coupling reaction of carboxylic acids and isonitriles under mild conditions.
作者信息
Wu Xiangyang, Li Xuechen, Danishefsky Samuel J
机构信息
Laboratory for Bioorganic Chemistry, Sloan-Kettering Institute for Cancer Research, 1275 York Avenue, New York, NY 10065, USA.
出版信息
Tetrahedron Lett. 2009 Apr 8;50(14):1523-1525. doi: 10.1016/j.tetlet.2009.01.046.
Abstract
The coupling reaction between carboxylic acids and isonitriles in the presence of thio phenol as activator under mild conditions is described.
摘要
描述了在温和条件下，以硫酚作为活化剂时羧酸与异腈之间的偶联反应。
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本文引用的文献
1
Noncatalytic reaction of isonitriles and carboxylic acids en route to amide-type linkages.异腈与羧酸在形成酰胺型键的过程中的非催化反应。
Nat Protoc. 2008;3(10):1666-70. doi: 10.1038/nprot.2008.153.
2
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J Am Chem Soc. 2008 Oct 8;130(40):13225-7. doi: 10.1021/ja804709s. Epub 2008 Sep 11.
3
On the two-component microwave-mediated reaction of isonitriles with carboxylic acids: regarding alleged formimidate carboxylate mixed anhydrides.关于异腈与羧酸的双组分微波介导反应：论所谓的甲脒羧酸混合酸酐
J Am Chem Soc. 2008 Oct 8;130(40):13222-4. doi: 10.1021/ja8047078. Epub 2008 Sep 11.
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New chemistry with old functional groups: on the reaction of isonitriles with carboxylic acids--a route to various amide types.含旧官能团的新化学：异腈与羧酸的反应——通往各类酰胺的途径
J Am Chem Soc. 2008 Apr 23;130(16):5446-8. doi: 10.1021/ja800612r. Epub 2008 Mar 28.
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