Mbouangouere R N, Tane P, Ngamga D, Djemgou P, Choudhary M I, Ngadjui B T
Department of Chemistry, Faculty of Science, University of Dschang, Box 67 Dschang, Cameroon.
Afr J Tradit Complement Altern Med. 2007 Feb 16;4(3):294-8.
A new glyceryl derivative (Glyceryl-1-hexacosanoate) and a flavone derivative (methyletherapigenin) were isolated from the stem bark extract of Piptadenia africana, a western Cameroonian plant species. Common terpenes like sitosterol, beta-amyrin and eicosane were also isolated. These compounds were identified using physical and spectroscopic methods including mp, IR, (1)H and (13)C-NMR, DEPT, COSY, HMQC, HMBC, EI MS, HREI MS as well as some chemical transformations. The antibacterial activity of the extract, the fractions and the pure compounds is also discussed.
从喀麦隆西部植物物种非洲球花豆的茎皮提取物中分离出一种新的甘油衍生物(1-二十六烷酸甘油酯)和一种黄酮衍生物(甲基醚芹菜素)。还分离出了常见的萜类化合物,如甾醇、β-香树脂醇和二十烷。这些化合物通过熔点、红外光谱、氢核磁共振(¹H-NMR)、碳核磁共振(¹³C-NMR)、无畸变极化转移增强法(DEPT)、化学位移相关谱(COSY)、异核多量子相干谱(HMQC)、异核多键相关谱(HMBC)、电子轰击质谱(EI MS)、高分辨电子轰击电离质谱(HREI MS)等物理和光谱方法以及一些化学转化进行鉴定。还讨论了提取物、馏分和纯化合物的抗菌活性。