Millogo-Kone H, Guissou Ip, Nacoulma O, Traore A S
Centre National de la Recherche Scientifique et Technologique, Institut de Recherche en Sciences de la Santé, Département Médecine et Pharmacopée Traditionnelles-Pharmacie, Ouagadougou 03, Burkina Faso.
Afr J Tradit Complement Altern Med. 2007 Jun 10;4(4):392-6. doi: 10.4314/ajtcam.v4i4.31234.
Total and hydroalcoholic extracts of the stem barks of Parkia biglobosa (Jacq) Benth. (Mimosaceae) were tested on strains belonging to three species of Shigellae: S. dysenteriae, S. flexneri and S. boydii collected from hospitals in Ouagadougou, Burkina Faso. The results showed that both extracts were active against Shigellae. The hydroalcoholic extract was more active than the decoction (aqueous one) prescribed by the traditional healer. Both extracts were particularly effective against S. dysenteriae, the most virulent of the three pathogenic species. The effects of the extracts have been compared to that of gentamicin. The phytochemical screening on the extracts revealed the presence of sterols, triterpenes, polyphenolic compounds including tannins, flavonoids, coumarins, anthocyanidins. Other components are saponosides and reducing sugars.
痢疾志贺氏菌、福氏志贺氏菌和鲍氏志贺氏菌，测试了球花豆（Parkia biglobosa (Jacq) Benth.，含羞草科）茎皮的总提取物和水醇提取物。结果表明，两种提取物对志贺氏菌均有活性。水醇提取物比传统治疗师开的煎剂（水剂）活性更强。两种提取物对三种致病物种中毒力最强的痢疾志贺氏菌特别有效。已将提取物的效果与庆大霉素的效果进行了比较。对提取物的植物化学筛选显示存在甾醇、三萜、包括单宁、黄酮类、香豆素、花青素的多酚化合物。其他成分是皂苷和还原糖。
