Millogo-Kone H, Guissou I P, Nacoulma O, Traore A S
Centre National de la Recherche Scientifique et Technologique, Institut de Recherche en Sciences de la Santé, Département Médecine et Pharmacopée Traditionnelles-Pharmacie.
Afr J Tradit Complement Altern Med. 2008 Apr 10;5(3):238-43. doi: 10.4314/ajtcam.v5i3.31279.
Hydroethanolic and aqueous extracts of leaf and stem bark of Parkia biglobosa (Jacq) Benth. (Mimosaceae) were tested against clinical isolates Escherichia coli, Salmonella typhi, Shigella dysenteriae and Enterococcus faecalis, and corresponding collection strains E. coli CIP 105 182, Salmonella enterica CIP 105 150, Shigella dysenteriae CIP 54-51 and Enterococcus faecalis CIP 103 907. Discs of Gentamicin, a broad spectrum antibiotic were used as positive controls. The results showed that all the extracts possess antimicrobial activities. A comparative study of the antibacterial activity of the leaves and that of the bark showed that for all the tested microorganisms, the hydroalcoholic extract of the bark is more active than the aqueous extract of the leaf. The hydroethanolic extract of the leaves is as effective as the aqueous extract of the stem bark prescribed by the traditional healer, suggesting it is possible to use leaves other than the roots and bark. The phytochemical screening showed that sterols and triterpenes, saponosides, tannins, reducing compounds, coumarins, anthocyanosides, flavonosides are present in both bark and leaf but in different concentrations.
对球花豆（Parkia biglobosa (Jacq) Benth.，含羞草科）叶和茎皮的乙醇水提取物及水提取物，针对临床分离株大肠杆菌、伤寒沙门氏菌、痢疾志贺氏菌和粪肠球菌，以及相应的保藏菌株大肠杆菌CIP 105 182、肠炎沙门氏菌CIP 105 150、痢疾志贺氏菌CIP 54 - 51和粪肠球菌CIP 103 907进行了测试。使用广谱抗生素庆大霉素圆片作为阳性对照。结果表明，所有提取物均具有抗菌活性。对叶和树皮抗菌活性的比较研究表明，对于所有测试微生物，树皮的乙醇水提取物比叶的水提取物活性更强。叶的乙醇水提取物与传统治疗师所开茎皮水提取物的效果相当，这表明除了根和树皮之外，叶也有可能被利用。植物化学筛选显示，树皮和叶中均含有甾醇、三萜、皂苷、单宁、还原性化合物、香豆素、花色苷、黄酮苷，但浓度不同。
