牛膝根的雌激素及抗孕作用
Estrogenic and pregnancy interceptory effects of Achyranthes aspera Linn. root.
作者信息
Vasudeva Neeru, Sharma S K
机构信息
Pharmacognosy Division, Faculty of Pharmaceutical Sciences, Guru Jambheshwar University, Hisar-125001, India.
出版信息
Afr J Tradit Complement Altern Med. 2006 Aug 28;4(1):7-11. doi: 10.4314/ajtcam.v4i1.31185.
Abstract
Achyranthes aspera Linn. (Amaranthaceae) is an abundant indigenous herb in India. It is traditionally being used as an abortifacient. Four successive solvent extracts of the root were screened for antifertility activity in female albino rats. The chloroform and ethanol extracts exhibited 100% anti-implantation activity when given orally at 200 mg/kg body weight. Both the extracts at the dose of 200 mg/kg body weight also exhibited estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity.
摘要
牛筋草（苋科）是印度一种常见的本土草本植物。传统上它被用作堕胎药。对牛筋草根的四种连续溶剂提取物进行了雌性白化大鼠抗生育活性筛选。氯仿提取物和乙醇提取物以200毫克/千克体重口服给药时，显示出100%的抗着床活性。两种提取物在200毫克/千克体重剂量下也表现出雌激素活性。对子宫进行了组织学研究以证实这种雌激素活性。
相似文献
1
Estrogenic and pregnancy interceptory effects of Achyranthes aspera Linn. root.牛膝根的雌激素及抗孕作用
Afr J Tradit Complement Altern Med. 2006 Aug 28;4(1):7-11. doi: 10.4314/ajtcam.v4i1.31185.
2
Post-coital antifertility activity of Achyranthes aspera Linn. root.倒扣草根的性交后抗生育活性。
J Ethnopharmacol. 2006 Sep 19;107(2):179-81. doi: 10.1016/j.jep.2006.03.009. Epub 2006 Mar 22.
3
Abortifacient principle of Achyranthes aspera Linn.牛膝的堕胎原理
Indian J Exp Biol. 1977 Oct;15(10):856-8.
4
Effect of Achyranthes aspera L. on fetal abortion, uterine and pituitary weights, serum lipids and hormones.牛鞭草对胎儿流产、子宫和垂体重量、血脂及激素的影响。
Afr Health Sci. 2006 Jun;6(2):108-12. doi: 10.5555/afhs.2006.6.2.108.
5
Anticonvulsant activity and acute neurotoxic profile of Achyranthes aspera Linn.牛膝的抗惊厥活性和急性神经毒性特征
J Ethnopharmacol. 2017 Apr 18;202:97-102. doi: 10.1016/j.jep.2017.03.018. Epub 2017 Mar 14.
6
Study of CNS depressant and behavioral activity of an ethanol extract of Achyranthes Aspera (Chirchita) in mouse model.牛膝乙醇提取物对小鼠模型中枢神经系统的抑制作用及行为活性研究。
Ann Neurosci. 2011 Apr;18(2):44-7. doi: 10.5214/ans.0972.7531.1118204.
7
Antifertility activity of Derris brevipes variety coriacea.短叶鱼藤厚叶变种的抗生育活性。
J Ethnopharmacol. 2003 Jan;84(1):99-104. doi: 10.1016/s0378-8741(02)00288-x.
8
Study of central nervous system depressant and behavioral activity of an ethanol extract of Achyranthes aspera (Agadha) in different animal models.牛膝乙醇提取物在不同动物模型中的中枢神经系统抑制作用及行为活性研究。
Int J Appl Basic Med Res. 2011 Jul;1(2):104-8. doi: 10.4103/2229-516X.91154.
9
Antifertility activity of Striga orobanchioides.独脚金的抗生育活性。
Biol Pharm Bull. 1994 Aug;17(8):1029-31. doi: 10.1248/bpb.17.1029.
10
Antifertility screening of plants. Part IX. Effect of five indigenous plants on early pregnancy in female albino rats.植物的抗生育筛选。第九部分。五种本土植物对雌性白化大鼠早期妊娠的影响。
Indian J Med Res. 1974 Jun;62(6):831-7.
引用本文的文献
1
Estrogenic post-menopausal anti-osteoporotic mechanism of L.: Phytochemicals and network pharmacology approaches.L.的雌激素样绝经后抗骨质疏松机制：植物化学物质与网络药理学方法
Heliyon. 2024 Oct 2;10(20):e38792. doi: 10.1016/j.heliyon.2024.e38792. eCollection 2024 Oct 30.
2
Antifertility activity of aqueous ethanolic extract of Hymenocardia acida stem bark in female rats.酸膜叶海桐茎皮水乙醇提取物对雌性大鼠的抗生育活性。
Iran J Reprod Med. 2011 Summer;9(3):217-22.
3
Antifertility effects of Pouzolzia mixta in female Wistar rats.混合雾水葛对雌性Wistar大鼠的抗生育作用。
Afr J Tradit Complement Altern Med. 2013 Apr 12;10(3):526-32. eCollection 2013.
本文引用的文献
1
In vitro determination of the contraceptive spermicidal activity of a composite extract of Achyranthes aspera and Stephania hernandifolia on human semen.体外测定牛膝和粪箕笃复合提取物对人类精液的杀精避孕活性。
Contraception. 2006 Mar;73(3):284-8. doi: 10.1016/j.contraception.2005.07.014. Epub 2005 Oct 20.
2
Stimulation of immunity in Indian major carp Catla catla with herbal feed ingredients.用草药饲料成分刺激印度主要鲤鱼印度鲶的免疫力。
Fish Shellfish Immunol. 2005 Apr;18(4):327-34. doi: 10.1016/j.fsi.2004.08.005.
3
Impact of feeding ethanolic extracts of Achyranthes aspera Linn. on reproductive functions in male rats.
Indian J Exp Biol. 2002 Nov;40(11):1307-9.
4
Effect of alcohol extract of Achyranthes aspera Linn. on acute and subacute inflammation.牛鞭草乙醇提取物对急性和亚急性炎症的影响。
需要说明的是，你提供的原文中“Achyranthes aspera Linn.”常见中文名是牛鞭草，而非牛膝，我按照正确的植物名称进行了翻译，若这与你的预期不符，请以你实际需求为准。
Phytother Res. 2003 Jan;17(1):77-9. doi: 10.1002/ptr.1070.
5
Achyranthes aspera elevates thyroid hormone levels and decreases hepatic lipid peroxidation in male rats.牛鞭草可提高雄性大鼠的甲状腺激素水平，并降低其肝脏脂质过氧化水平。
J Ethnopharmacol. 2000 Aug;71(3):527-32. doi: 10.1016/s0378-8741(00)00170-7.
6
Contraceptive and hormonal properties of Achyranthes aspera in rats and hamsters.
Planta Med. 1986 Jun(3):231-3.
7
Evaluation of the hypoglycaemic effect of Achyranthes aspera in normal and alloxan-diabetic rabbits.
J Ethnopharmacol. 1991 Jan;31(1):49-57. doi: 10.1016/0378-8741(91)90143-2.
Zotero 插件