Hiremath S P, Badami S, Swamy H K, Patil S B, Londonkar R L
Department of Chemistry, Gulbarga University, India.
Biol Pharm Bull. 1994 Aug;17(8):1029-31. doi: 10.1248/bpb.17.1029.
Four successive solvent extracts of the whole plant Striga orobanchioides have been screened for antifertility activity in albino rats. Of these the ethanolic extract was found to be most effective in causing significant anti-implantation activity. The antifertility activity was reversible on withdrawal of treatment with the extract. The ethanolic extract at 200 mg/kg showed estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity.
对独脚金全草的四种连续溶剂提取物进行了对白化大鼠抗生育活性的筛选。其中,乙醇提取物在引起显著抗着床活性方面被发现最为有效。提取物治疗停止后,抗生育活性是可逆的。200mg/kg的乙醇提取物表现出雌激素活性。对子宫进行了组织学研究以证实这种雌激素活性。