一些喀麦隆药用植物粗提物的抗疟活性。
Antimalarial activity in crude extracts of some Cameroonian medicinal plants.
作者信息
Bickii Jean, Tchouya Guy Raymond Feuya, Tchouankeu Jean Claude, Tsamo Etienne
机构信息
Institute for Medical Research and the studies of Medicinal Plants (IMPM), Laboratoire de Recherches sur le Paludisme, Yaoundé, Cameroon.
出版信息
Afr J Tradit Complement Altern Med. 2006 Aug 28;4(1):107-11. doi: 10.4314/ajtcam.v4i1.31200.
Abstract
Fifteen crude extracts from the stem bark and seeds of four medicinal plants, viz: Entandrophragma angolense, Picralima nitida, Schumanniophyton magnificum and Thomandersia hensii were tested in vitro for their antimalarial activity against the chloroquine-resistant Plasmodium falciparum W2 strain. The results showed that the extracts of these plants possessed some antimalarial activity, the methanol extract of Picralima nitida demonstrating the highest activity in vitro. Further isolation and identification of some active compounds from these plants will justify their common use in traditional medicine for the treatment of malaria or fever in Cameroon.
摘要
对四种药用植物，即安哥拉Entandrophragma、光亮 Picralima、壮丽Schumanniophyton和亨氏Thomandersia的茎皮和种子的15种粗提物进行了体外测试，以检测它们对氯喹耐药恶性疟原虫W2株的抗疟活性。结果表明，这些植物的提取物具有一定的抗疟活性，其中光亮Picralima的甲醇提取物在体外表现出最高活性。从这些植物中进一步分离和鉴定一些活性化合物，将证明它们在喀麦隆传统医学中用于治疗疟疾或发烧的普遍用途是合理的。
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