• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

N-acetylcysteine (NAC) in young marijuana users: an open-label pilot study.

作者信息

Gray Kevin M, Watson Noreen L, Carpenter Matthew J, Larowe Steven D

出版信息

Am J Addict. 2010 Mar-Apr;19(2):187-9. doi: 10.1111/j.1521-0391.2009.00027.x.

DOI:10.1111/j.1521-0391.2009.00027.x
PMID:20163391
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2826714/
Abstract
摘要

相似文献

1
N-acetylcysteine (NAC) in young marijuana users: an open-label pilot study.年轻大麻使用者中的N-乙酰半胱氨酸（NAC）：一项开放标签的试点研究。
Am J Addict. 2010 Mar-Apr;19(2):187-9. doi: 10.1111/j.1521-0391.2009.00027.x.
2
Achieving cannabis cessation -- evaluating N-acetylcysteine treatment (ACCENT): design and implementation of a multi-site, randomized controlled study in the National Institute on Drug Abuse Clinical Trials Network.实现大麻戒断——评估N-乙酰半胱氨酸治疗（ACCENT）：美国国立药物滥用研究所临床试验网络中一项多中心随机对照研究的设计与实施
Contemp Clin Trials. 2014 Nov;39(2):211-23. doi: 10.1016/j.cct.2014.08.011. Epub 2014 Aug 30.
3
A double-blind randomized controlled trial of N-acetylcysteine in cannabis-dependent adolescents.N-乙酰半胱氨酸治疗大麻依赖青少年的双盲随机对照试验。
Am J Psychiatry. 2012 Aug;169(8):805-12. doi: 10.1176/appi.ajp.2012.12010055.
4
Alcohol use during a trial of N-acetylcysteine for adolescent marijuana cessation.青少年大麻戒断的N-乙酰半胱氨酸试验期间的酒精使用情况。
Addict Behav. 2016 Dec;63:172-7. doi: 10.1016/j.addbeh.2016.08.001. Epub 2016 Aug 4.
5
Low Pretreatment Impulsivity and High Medication Adherence Increase the Odds of Abstinence in a Trial of N-Acetylcysteine in Adolescents with Cannabis Use Disorder.在一项针对大麻使用障碍青少年的N-乙酰半胱氨酸试验中，治疗前低冲动性和高药物依从性增加了戒酒的几率。
J Subst Abuse Treat. 2016 Apr;63:72-7. doi: 10.1016/j.jsat.2015.12.003. Epub 2015 Dec 28.
6
A randomized placebo-controlled trial of N-acetylcysteine for cannabis use disorder in adults.一项针对成年人大麻使用障碍的N-乙酰半胱氨酸随机安慰剂对照试验。
Drug Alcohol Depend. 2017 Aug 1;177:249-257. doi: 10.1016/j.drugalcdep.2017.04.020. Epub 2017 Jun 10.
7
Cigarette smoking during an N-acetylcysteine-assisted cannabis cessation trial in adolescents.青少年N-乙酰半胱氨酸辅助大麻戒断试验期间的吸烟情况。
Am J Drug Alcohol Abuse. 2014 Jul;40(4):285-91. doi: 10.3109/00952990.2013.878718. Epub 2014 Apr 10.
8
Cognitive performance in a placebo-controlled pharmacotherapy trial for youth with marijuana dependence.一项针对大麻依赖青少年的安慰剂对照药物治疗试验中的认知表现。
Addict Behav. 2015 Jun;45:119-23. doi: 10.1016/j.addbeh.2015.01.013. Epub 2015 Jan 23.
9
The role of depressive symptoms in treatment of adolescent cannabis use disorder with N-Acetylcysteine.抑郁症状在使用 N-乙酰半胱氨酸治疗青少年大麻使用障碍中的作用。
Addict Behav. 2018 Oct;85:26-30. doi: 10.1016/j.addbeh.2018.05.014. Epub 2018 May 21.
10
The effect of N-acetylcysteine on alcohol use during a cannabis cessation trial.N-乙酰半胱氨酸对大麻戒断试验期间饮酒的影响。
Drug Alcohol Depend. 2018 Apr 1;185:17-22. doi: 10.1016/j.drugalcdep.2017.12.005. Epub 2018 Feb 1.

引用本文的文献

1
The Potential of N-acetyl Cysteine in Behavioral Addictions and Related Compulsive and Impulsive Behaviors and Disorders: a Scoping Review.N-乙酰半胱氨酸在行为成瘾及相关强迫和冲动行为与障碍中的潜力：一项范围综述
Curr Addict Rep. 2022 Dec;9(4):660-670. doi: 10.1007/s40429-022-00446-3. Epub 2022 Sep 29.
2
Old Dog, New Tricks: A Review of Identifying and Addressing Youth Cannabis Vaping in the Pediatric Clinical Setting.老狗学新招：儿科临床环境中识别和应对青少年大麻雾化问题的综述
Clin Med Insights Pediatr. 2023 Mar 25;17:11795565231162297. doi: 10.1177/11795565231162297. eCollection 2023.
3
Treatment of Adolescent Cannabis Use Disorders.青少年大麻使用障碍的治疗。
Child Adolesc Psychiatr Clin N Am. 2023 Jan;32(1):141-155. doi: 10.1016/j.chc.2022.07.006. Epub 2022 Oct 22.
4
Clearing up the smoke: Physical and mental health considerations regarding cannabis use in adolescents with cystic fibrosis.厘清迷雾：囊性纤维化青少年使用大麻的身心健康问题。
Pediatr Pulmonol. 2023 Feb;58(2):398-407. doi: 10.1002/ppul.26241. Epub 2022 Nov 18.
5
Solid phase wax coating of -acetylcysteine (NAC) to decrease its solubility profile as a ready to mix supplement.对乙酰半胱氨酸（NAC）进行固相蜡包衣，以降低其溶解度，使其成为一种即混型补充剂。
RSC Adv. 2022 Jun 14;12(27):17550-17558. doi: 10.1039/d1ra09279k. eCollection 2022 Jun 7.
6
Stress- and drug-induced neuroimmune signaling as a therapeutic target for comorbid anxiety and substance use disorders.应激和药物诱导的神经免疫信号作为共病焦虑和物质使用障碍的治疗靶点。
Pharmacol Ther. 2022 Nov;239:108212. doi: 10.1016/j.pharmthera.2022.108212. Epub 2022 May 14.
7
Natural and synthetic estrogens specifically alter nicotine demand and cue-induced nicotine seeking in female rats.天然和合成雌激素特异性改变雌性大鼠的尼古丁需求和线索诱导的尼古丁觅药行为。
Neuropharmacology. 2021 Oct 15;198:108756. doi: 10.1016/j.neuropharm.2021.108756. Epub 2021 Aug 17.
8
Adolescent exposure to delta-9-tetrahydrocannabinol and ethanol heightens sensitivity to fear stimuli.青少年接触大麻二酚和乙醇会提高对恐惧刺激的敏感程度。
Behav Brain Res. 2021 Oct 11;415:113517. doi: 10.1016/j.bbr.2021.113517. Epub 2021 Aug 10.
9
Fetal Neuroprotective Strategies: Therapeutic Agents and Their Underlying Synaptic Pathways.胎儿神经保护策略：治疗药物及其潜在的突触途径。
Front Synaptic Neurosci. 2021 Jun 23;13:680899. doi: 10.3389/fnsyn.2021.680899. eCollection 2021.
10
Evaluating N-acetylcysteine for early and end-of-treatment abstinence in adult cigarette smokers.评估 N-乙酰半胱氨酸对成年吸烟人群戒烟早期和治疗结束时的作用。
Drug Alcohol Depend. 2021 Aug 1;225:108815. doi: 10.1016/j.drugalcdep.2021.108815. Epub 2021 Jun 18.

本文引用的文献

1
Challenges in quantifying marijuana use.量化大麻使用情况的挑战。
Am J Addict. 2009 Mar-Apr;18(2):178-9. doi: 10.1080/10550490902772579.
2
A preliminary trial: double-blind comparison of nefazodone, bupropion-SR, and placebo in the treatment of cannabis dependence.一项初步试验：奈法唑酮、安非他酮缓释剂与安慰剂治疗大麻依赖的双盲比较
Am J Addict. 2009 Jan-Feb;18(1):53-64. doi: 10.1080/10550490802408936.
3
The role of cystine-glutamate exchange in nicotine dependence in rats and humans.胱氨酸-谷氨酸交换在大鼠和人类尼古丁依赖中的作用。
Biol Psychiatry. 2009 May 15;65(10):841-5. doi: 10.1016/j.biopsych.2008.10.040. Epub 2008 Dec 21.
4
Blunted cystine-glutamate antiporter function in the nucleus accumbens promotes cocaine-induced drug seeking.伏隔核中胱氨酸-谷氨酸反向转运体功能减弱会促进可卡因诱导的觅药行为。
Neuroscience. 2008 Aug 13;155(2):530-7. doi: 10.1016/j.neuroscience.2008.06.010. Epub 2008 Jun 10.
5
Glutamatergic substrates of drug addiction and alcoholism.药物成瘾和酒精中毒的谷氨酸能底物。
Biochem Pharmacol. 2008 Jan 1;75(1):218-65. doi: 10.1016/j.bcp.2007.06.039. Epub 2007 Jun 30.
6
Assessment of cannabis craving using the Marijuana Craving Questionnaire.使用大麻渴求问卷评估大麻渴求。
Methods Mol Med. 2006;123:209-16. doi: 10.1385/1-59259-999-0:209.
7
Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals.N-乙酰半胱氨酸在可卡因依赖个体中的安全性和耐受性
Am J Addict. 2006 Jan-Feb;15(1):105-10. doi: 10.1080/10550490500419169.
8
Pharmacotherapy for marijuana dependence: a double-blind, placebo-controlled pilot study of divalproex sodium.大麻依赖的药物治疗：丙戊酸钠的双盲、安慰剂对照试验研究
Am J Addict. 2004 Jan-Feb;13(1):21-32. doi: 10.1080/10550490490265280.
9
Differentiating new marijuana use from residual drug excretion in occasional marijuana users.区分偶尔使用大麻者中新近使用大麻的情况与残留药物排泄情况。
J Anal Toxicol. 1998 Oct;22(6):445-54. doi: 10.1093/jat/22.6.445.