Gauwerky Katharina J, Ehrenfeld Michael, Bakos Renato M, Volkenandt Matthias, Ruzicka Thomas, Berking Carola
Klinik und Poliklinik für Dermatologie und Allergologie, LMU München.
J Dtsch Dermatol Ges. 2010 Aug;8(8):614-6. doi: 10.1111/j.1610-0387.2010.07347.x. Epub 2010 Feb 15.
Melanoma of the oral mucosa is an extremely rare tumor. At the time of diagnosis most melanomas are in an advanced stage because of few clinical signs. Therefore the prognosis of melanoma of the oral mucosa is often very poor. We present a 48-year-old patient with melanoma of the oral mucosa first diagnosed 22 years ago. Over 20 years several wide excisions were necessary because of multiple local relapses. Eventually, the patient died from brain metastases.
口腔黏膜黑色素瘤是一种极为罕见的肿瘤。在诊断时,由于临床症状较少,大多数黑色素瘤已处于晚期。因此,口腔黏膜黑色素瘤的预后通常很差。我们报告一位48岁的口腔黏膜黑色素瘤患者,该患者于22年前首次确诊。20多年来,由于多次局部复发,需要进行多次广泛切除。最终,患者死于脑转移。