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一例罕见侵袭性口腔恶性黑色素瘤病例报告。

Report of a rare and aggressive case of oral malignant melanoma.

作者信息

Ahmadi-Motamayel Fatemeh, Falsafi Parisa, Baghaei Fahimeh

机构信息

Research Center for Molecular Medicine, Department of Oral Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

出版信息

Oral Maxillofac Surg. 2013 Mar;17(1):47-51. doi: 10.1007/s10006-012-0311-3. Epub 2012 Feb 25.

DOI:10.1007/s10006-012-0311-3
PMID:22367683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3576568/
Abstract

BACKGROUND

Oral melanoma is a very rare malignancy with unknown etiology. Its higher incidence is between 41 and 60 years of age. A high localization of oral melanoma was found in the maxilla. Gender distribution was reported as 1:1. Oral melanoma represents 0.2% to 8% of the all the total cases of melanoma of the body.

CASE REPORT

In this article we report an aggressive case of oral melanoma in a 71-year-old male with chief complaint of black swelling of the gingiva, paresthesia, and denture ill fitting.

DISCUSSION

Most oral melanomas are asymptomatic and painless in early stages and unfortunately diagnosis delayed until symptoms occurred. Early detection of suspected melanotic lesions by patient, dentist, and physician is very important.

摘要

背景

口腔黑色素瘤是一种病因不明的极为罕见的恶性肿瘤。其高发年龄段在41至60岁之间。口腔黑色素瘤在上颌骨中的定位较高。据报道，其性别分布为1:1。口腔黑色素瘤占全身黑色素瘤病例总数的0.2%至8%。

病例报告

在本文中，我们报告了一例侵袭性口腔黑色素瘤病例，患者为一名71岁男性，主要症状为牙龈黑色肿胀、感觉异常和义齿佩戴不适。

讨论

大多数口腔黑色素瘤在早期无症状且无痛，不幸的是，诊断往往延迟到出现症状时。患者、牙医和医生早期发现可疑黑色素病变非常重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/b93c67b5f7b0/10006_2012_311_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/47f9d4523ae7/10006_2012_311_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/8089abd05d01/10006_2012_311_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/06748caa19c8/10006_2012_311_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/4a3d98d7b637/10006_2012_311_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/27581148e641/10006_2012_311_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/b93c67b5f7b0/10006_2012_311_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/47f9d4523ae7/10006_2012_311_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/8089abd05d01/10006_2012_311_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/06748caa19c8/10006_2012_311_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/4a3d98d7b637/10006_2012_311_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/27581148e641/10006_2012_311_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbe2/3576568/b93c67b5f7b0/10006_2012_311_Fig6_HTML.jpg

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BMC Res Notes. 2015 Sep 29;8:499. doi: 10.1186/s13104-015-1459-3.
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