采用短期直接观察治疗法（DOTS）进行治疗的患者的治疗结果。
Treatment outcomes of patients placed on treatment under directly observed therapy short-course (dots).
作者信息
Kaur Gurpreet, Goel N K, Kumar Dinesh, Janmeja A K, Swami H M, Kalia Meenu
机构信息
Deptt. of Community Medicine, Govt. Medical College, Chandigarh, India.
出版信息
Lung India. 2008 Apr;25(2):75-7. doi: 10.4103/0970-2113.44124.
BACKGROUND
Tuberculosis continues to be a pressing health problem in India. The Revised National Tuberculosis Programme (RNTCP), an application of Directly Observed Treatment Short-course (DOTS) in India, launched in 1997 needs continuous evaluation.
OBJECTIVE
To study the outcomes of treatment among the patients put on DOTS under RNTCP in Chandigarh, UT. MATERIAL #ENTITYSTARTX00026;
METHODS
A Longitudinal study was conducted during 2004-2005 in 13 Microscopic centres (MC's) spread over 2 Tuberculosis Units (TU's) under District Tuberculosis Centre (DTC) in Union Territory (UT), Chandigarh. A sample of 265 respondents, selected by two-stage stratified random sampling technique, was recruited in the study cohort. Data analysis was done using SPSS-10 statistical software package.
RESULTS
For Category I and Category II patients, the Success rate was 98.6% and 90.4% respectively. The overall default rate was 1.1% and failure rate was 2.6%. For re-treatment cases, failure rate was higher i.e. 5.8%. The sputum conversion rate among the new smear positive cases was 93.8% at 3 months of treatment. For the re-treatment cases, spu-tum conversion rate at 3 months was 94.1%.
CONCLUSION
The study concludes that RNTCP is running successfully in UT Chandigarh, having high success rate and low default rate. The reasons for high failure rate should be explored in depth.
背景
在印度，结核病仍然是一个紧迫的健康问题。1997年启动的印度修订国家结核病规划（RNTCP）是直接观察短程治疗（DOTS）在印度的应用，需要持续评估。
目的
研究在昌迪加尔联合属地接受RNTCP下DOTS治疗的患者的治疗结果。材料与方法：2004 - 2005年在昌迪加尔联合属地（UT）地区结核病中心（DTC）下属的2个结核病单元（TU）的13个显微镜中心（MC）进行了一项纵向研究。采用两阶段分层随机抽样技术选取265名受访者作为研究队列。使用SPSS - 10统计软件包进行数据分析。
结果
I类和II类患者的成功率分别为98.6%和90.4%。总体违约率为1.1%，失败率为2.6%。复治病例的失败率较高，即5.8%。新涂片阳性病例在治疗3个月时的痰菌转阴率为93.8%。复治病例在3个月时的痰菌转阴率为94.1%。
结论
该研究得出结论，RNTCP在昌迪加尔联合属地运行成功，成功率高且违约率低。应深入探究高失败率的原因。
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