Department of Orthopaedic Surgery, University General Hospital of Alexandroupolis, Dragana, Alexandroupolis, Greece.
Arch Orthop Trauma Surg. 2010 Jun;130(6):733-7. doi: 10.1007/s00402-010-1062-y. Epub 2010 Feb 18.
The aim of this study was to evaluate the efficacy of two different autotransfusion methods in total knee replacement (TKR) performed without tourniquet, in comparison to allogeneic blood transfusion (ABT) only.
In a comparative study, 248 patients with knee osteoarthritis were randomized in three groups: in control Group 85 the patients underwent only ABT post-operatively, in Group 1 (n:92) an intraoperative and postoperative autotransfusion were utilized, and in Group 2 (n:71) only a postoperative autotransfusion was applied. Post-operative ABT was utilized according to predetermined criteria.
Comparing Group 0 to Group 1 and 2 the difference in need for ABT post-operatively was statistically highly significant (p < 0.001) even when the results were analyzed classifying the patients according to the preoperative Hb levels. The difference between Group 1 and 2 was not significant.
According to the results of this study, auto-transfusion reduces the need for ABT in TKR performed without tourniquet.
本研究旨在评估在不使用止血带的全膝关节置换术（TKR）中，与仅异体输血（ABT）相比，两种不同自体输血方法的疗效。
在一项比较研究中，248 例膝关节骨关节炎患者随机分为三组：对照组 85 例患者术后仅接受 ABT，组 1（n：92）术中及术后均采用自体输血，组 2（n：71）仅术后进行自体输血。根据预定标准，术后需要 ABT。
与组 0 相比，组 1 和 2 术后需要 ABT 的差异具有统计学意义（p<0.001），即使根据术前 Hb 水平对患者进行分类分析，结果也是如此。组 1 和 2 之间的差异无统计学意义。
根据这项研究的结果，自体输血可减少无止血带 TKR 术后对 ABT 的需求。
