Orwin J F, Fisher R C, Wiedel J D
Department of Surgery, University of Wisconsin, Madison 53792.
J Arthroplasty. 1991 Mar;6(1):1-9. doi: 10.1016/s0883-5403(06)80151-8.
Osteonecrosis of the hip is a well known complication in renal transplantation patients who are treated with corticosteroids for immunosuppression. In a consecutive series of 10 patients with osteonecrosis of the hip, 16 primary uncemented bipolar endoprostheses were inserted between April 1984, and February 1986. The average follow-up period after surgery was 40 months, (range, 24-48 months). All patients developed osteonecrosis of their hips and were operated on within 2 years of their renal transplant. At the time of surgery, all patients were still taking corticosteroids as well as other immunosuppressants. The average age at surgery was 34.6 years (range, 21-48 years). All hips were classified as stage 3 or 4 before operation. The average Harris score at follow-up examination was 94.2 (range, 74-101), with 13 hips rated excellent, 1 hip rated good, and 1 hip rated fair. One patient's hip prosthesis was removed after 17 months secondary to a septic arthritis. This was the only major complication in this series. Pain was improved in all patients. However, postoperative limp and abductor weakness still presented a significant problem. An extensive radiographic evaluation was made on all hips. Eleven observations and measurements were made using radiographs of the pelvis and hip. Vertical subsidence was present in 33% of the hips and averaged 2.2 mm (range, 1-4 mm). No significant radiographic loosening was evident in any hip. Acetabular protrusio was evaluated in all patients, and was found to be less than 4 mm in either the superior or axial direction. Heterotopic ossification was present in 80% of hips, but resulted in loss of motion in only one hip.(ABSTRACT TRUNCATED AT 250 WORDS)
髋部骨坏死是肾移植患者接受皮质类固醇免疫抑制治疗时一种众所周知的并发症。在1984年4月至1986年2月期间,对连续10例髋部骨坏死患者植入了16个初次使用的非骨水泥双极假体。术后平均随访期为40个月(范围24 - 48个月)。所有患者均发生髋部骨坏死,并在肾移植后2年内接受了手术。手术时,所有患者仍在服用皮质类固醇以及其他免疫抑制剂。手术时的平均年龄为34.6岁(范围21 - 48岁)。术前所有髋关节均被分类为3期或4期。随访检查时的平均Harris评分为94.2(范围74 - 101),其中13个髋关节评定为优秀,1个髋关节评定为良好,1个髋关节评定为尚可。1例患者的髋关节假体在17个月后因化脓性关节炎而取出。这是该系列中唯一的主要并发症。所有患者的疼痛均有所改善。然而,术后跛行和外展肌无力仍然是一个显著问题。对所有髋关节进行了广泛的影像学评估。使用骨盆和髋关节X线片进行了11项观察和测量。33%的髋关节出现垂直下沉,平均下沉2.2毫米(范围1 - 4毫米)。任何髋关节均未发现明显的影像学松动。对所有患者评估髋臼内陷,发现其在上方或轴向方向均小于4毫米。80%的髋关节存在异位骨化,但仅1个髋关节导致活动受限。(摘要截断于250字)