Han Yueh-Ying, Dinse Gregg E, Davis Devra L
University of Pittsburgh Cancer Institute, Center for Environmental Oncology, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 5150 Centre Avenue, Pittsburgh, PA 15232, USA.
Int J Occup Environ Health. 2010 Jan-Mar;16(1):75-84. doi: 10.1179/107735210800546164.
Our study analyzed temporal and demographic patterns of non-Hodgkin's lymphoma (NHL) incidence in Pennsylvania and compared Pennsylvania time trends with national trends. Joinpoint and age-period-cohort analyses summarized sex- and race-specific NHL incidence time trends between 1985 and 2004. Ecologic analysis identified demographic factors associated with age-adjusted county-specific NHL incidence. NHL incidence in Pennsylvania increased annually: 1.6% and 2.5% in white and black men and 1.6% and 3.2% in white and black women. National trends were similar, except for smaller increases in white men. Diffuse lymphoma appeared to be the major contributor to the increases. NHL incidence was higher in Pennsylvania counties with greater percentages of urban residents. NHL incidence patterns in Pennsylvania were parallel to those seen nationally, with the highest rates occurring in white men and in persons residing in urban areas.
我们的研究分析了宾夕法尼亚州非霍奇金淋巴瘤（NHL）发病率的时间和人口统计学模式，并将宾夕法尼亚州的时间趋势与全国趋势进行了比较。Joinpoint分析和年龄-时期-队列分析总结了1985年至2004年间按性别和种族划分的NHL发病率时间趋势。生态分析确定了与年龄调整后的特定县NHL发病率相关的人口统计学因素。宾夕法尼亚州的NHL发病率逐年上升：白人男性和黑人男性分别为1.6%和2.5%，白人女性和黑人女性分别为1.6%和3.2%。全国趋势相似，只是白人男性的增幅较小。弥漫性淋巴瘤似乎是发病率上升的主要原因。宾夕法尼亚州城市居民比例较高的县NHL发病率更高。宾夕法尼亚州的NHL发病率模式与全国情况相似，发病率最高的是白人男性和城市居民。
