Institut de Réadaptation Gingras-Lindsay de Montréal, Montréal, Canada.
J Int Neuropsychol Soc. 2010 Mar;16(2):287-96. doi: 10.1017/S1355617709991329. Epub 2010 Feb 19.
We examined the capacity of patients with multiple sclerosis (MS) to attribute mental states to others and to identify cognitive abilities that subserve theory of mind (ToM). In this article, we report findings on 41 out-patients with diagnosed MS who underwent detailed neuropsychological and social-cognitive assessment. They were subdivided into a cognitively intact (n=15) and cognitively impaired (n=26) group according to their neuropsychological test results. Their results were compared with those of 20 age- and education-matched controls. MS patients with cognitive impairments were found to have more difficulties attributing mental states to others than did cognitively intact MS patients and normal controls on two ToM measures; short stories (Happé, Winner, & Brownell, 1998) and video clips (Ouellet, Bédirian, Charbonneau, & Scherzer, 2009). When attention, memory, and working memory were controlled, performance on the WAIS-III Picture Arrangement task accounted for 17.3% of the variance in performance on the video clips task. Performance on a WAIS-III index composed of Similarities and Comprehension subtests, accounted for 7.0% of the variance in performance on the short stories task. These results provide some preliminary information on the effect of MS-related cognitive deficits on the ability to attribute mental states to others.
我们考察了多发性硬化症（MS）患者将心理状态归因于他人的能力，并确定了支持心理理论（ToM）的认知能力。在本文中，我们报告了对 41 名接受详细神经心理学和社会认知评估的门诊多发性硬化症患者的发现。根据他们的神经心理学测试结果，他们被分为认知正常（n=15）和认知受损（n=26）组。他们的结果与 20 名年龄和教育程度匹配的对照组进行了比较。在两项 ToM 测量中，认知受损的 MS 患者比认知正常的 MS 患者和正常对照组更难以将心理状态归因于他人；短故事（Happé、Winner 和 Brownell，1998）和视频剪辑（Ouellet、Bédirian、Charbonneau 和 Scherzer，2009）。当控制注意力、记忆和工作记忆时，WAIS-III 图片排列任务的表现解释了视频剪辑任务表现的 17.3%。由相似性和理解子测试组成的 WAIS-III 指数的表现解释了短故事任务表现的 7.0%。这些结果提供了一些关于 MS 相关认知缺陷对归因于他人心理状态的能力的影响的初步信息。
