Zielonka Ł, Przewoski W, Gajecka M, Jakimiuk E, Gajecki M
Department of Veterinary Prevention and Feed Hygiene, Faculty of Veterinary Medicine, University of Warmia and Mazury in Olsztyn, Oczapowskiego 13, 10-718 Olsztyn, Poland.
Pol J Vet Sci. 2009;12(4):539-47.
One of the possibilities for estimating pancreas activity is the estimation of zymogene granule content in pancreatic follicular cells. In the present study, the degree of pancreatic activity was measured in piglets from sows receiving enzymatic stimulating complex throughout pregnancy and during the lactation period. The pancreas was collected for ultrastructural examination from 1-day-old and 21-day-old piglets. The enzyme preparation influenced the ultrastructural structure of the piglet pancreas, but the secretory cells in these animals did not confirm a more intensive course of creation and maturation processes. The accumulation of granules in extra-secretory pancreatic cells was observed, with a large volume of these granules and granular crinophagy observed in older piglets. The findings indicate a slow process of granule release, which may be the result of overproduction, lower requirements for enzymes contained in the granules, or both.
评估胰腺活性的一种可能性是评估胰腺滤泡细胞中酶原颗粒的含量。在本研究中,对整个孕期和哺乳期接受酶刺激复合物的母猪所产仔猪的胰腺活性程度进行了测量。从1日龄和21日龄仔猪采集胰腺用于超微结构检查。酶制剂影响了仔猪胰腺的超微结构,但这些动物的分泌细胞并未证实其产生和成熟过程有更强烈的进程。观察到胰腺非分泌细胞中有颗粒积累,在较大的仔猪中观察到大量此类颗粒和颗粒自噬现象。研究结果表明颗粒释放过程缓慢,这可能是颗粒过度产生、对颗粒中所含酶的需求降低或两者共同作用的结果。